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Hyperactivity, impulsivity, and inattention in boys with cleft lip and palate: relationship to ventromedial prefrontal cortex morphology

Overview of attention for article published in Journal of Neurodevelopmental Disorders, August 2010
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  • Good Attention Score compared to outputs of the same age (66th percentile)

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1 Wikipedia page
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1 Google+ user

Citations

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37 Dimensions

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45 Mendeley
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Title
Hyperactivity, impulsivity, and inattention in boys with cleft lip and palate: relationship to ventromedial prefrontal cortex morphology
Published in
Journal of Neurodevelopmental Disorders, August 2010
DOI 10.1007/s11689-010-9060-5
Pubmed ID
Authors

Peggy Nopoulos, Aaron D. Boes, Althea Jabines, Amy L. Conrad, John Canady, Lynn Richman, Jeffrey D. Dawson

Abstract

The purpose of this study is to evaluate quantitative structural measures of the ventromedial prefrontal cortex (vmPFC) in boys with isolated clefts of the lip and/or palate (ICLP) relative to a comparison group and to associate measures of brain structure with quantitative measures of hyperactivity, impulsivity, and inattentiveness. A total of 50 boys with ICLP were compared to 60 healthy boys without clefts. Magnetic resonance imaging brain scans were used to evaluate vmPFC structure. Parents and teachers provided quantitative measures of hyperactivity, impulsivity, and inattentiveness using the Pediatric Behavior Scale. Boys with ICLP had significantly higher ratings of hyperactivity/impulsivity/inattention (HII) and significantly increased volume of the right vmPFC relative to the comparison group. There was a direct relationship between HII score and vmPFC volume in both the ICLP group and control group, but the relationship was in the opposite direction: in ICLP, the higher the vmPFC volume, the higher the HII score; for the comparison group, the lower the vmPFC volume, the greater the HII score. The vmPFC is a region of the brain that governs behaviors of hyperactivity, impulsivity and inattention (HII). In boys with ICLP, there are higher levels of HII compared to the controls and this is directly related to a significantly enlarged volume of the right vmPFC. Enlargement of this region of the brain is therefore considered to be pathological in the ICLP group and supports the notion that abnormal brain structure (from abnormal brain development) is the underlying etiology for the abnormal behaviors seen in this population.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 2%
Brazil 1 2%
Unknown 43 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 20%
Student > Ph. D. Student 8 18%
Student > Master 8 18%
Researcher 4 9%
Student > Doctoral Student 2 4%
Other 4 9%
Unknown 10 22%
Readers by discipline Count As %
Medicine and Dentistry 12 27%
Psychology 9 20%
Neuroscience 4 9%
Engineering 3 7%
Social Sciences 3 7%
Other 4 9%
Unknown 10 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 May 2017.
All research outputs
#6,421,645
of 22,818,766 outputs
Outputs from Journal of Neurodevelopmental Disorders
#250
of 476 outputs
Outputs of similar age
#29,654
of 94,150 outputs
Outputs of similar age from Journal of Neurodevelopmental Disorders
#3
of 3 outputs
Altmetric has tracked 22,818,766 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 476 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.5. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 94,150 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.