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Mendeley readers
Attention Score in Context
| Title |
Gene expression profile of intramuscular muscle in Nellore cattle with extreme values of fatty acid
|
|---|---|
| Published in |
BMC Genomics, November 2016
|
| DOI | 10.1186/s12864-016-3232-y |
| Pubmed ID | |
| Authors |
Mariana P. Berton, Larissa F. S. Fonseca, Daniela F. J. Gimenez, Bruno L. Utembergue, Aline S. M. Cesar, Luiz L. Coutinho, Marcos Vinicius A. de Lemos, Carolyn Aboujaoude, Angélica S. C. Pereira, Rafael M. de O Silva, Nedenia B. Stafuzza, Fabieli L. B. Feitosa, Hermenegildo L. J. Chiaia, Bianca F. Olivieri, Elisa Peripolli, Rafael L. Tonussi, Daniel M. Gordo, Rafael Espigolan, Adrielle M. Ferrinho, Lenise F. Mueller, Lucia G. de Albuquerque, Henrique N. de Oliveira, Susan Duckett, Fernando Baldi |
| Abstract |
Fatty acid type in beef can be detrimental to human health and has received considerable attention in recent years. The aim of this study was to identify differentially expressed genes in longissimus thoracis muscle of 48 Nellore young bulls with extreme phenotypes for fatty acid composition of intramuscular fat by RNA-seq technique. Differential expression analyses between animals with extreme phenotype for fatty acid composition showed a total of 13 differentially expressed genes for myristic (C14:0), 35 for palmitic (C16:0), 187 for stearic (C18:0), 371 for oleic (C18:1, cis-9), 24 for conjugated linoleic (C18:2 cis-9, trans11, CLA), 89 for linoleic (C18:2 cis-9,12 n6), and 110 genes for α-linolenic (C18:3 n3) fatty acids. For the respective sums of the individual fatty acids, 51 differentially expressed genes for saturated fatty acids (SFA), 336 for monounsaturated (MUFA), 131 for polyunsaturated (PUFA), 92 for PUFA/SFA ratio, 55 for ω3, 627 for ω6, and 22 for ω6/ω3 ratio were identified. Functional annotation analyses identified several genes associated with fatty acid metabolism, such as those involved in intra and extra-cellular transport of fatty acid synthesis precursors in intramuscular fat of longissimus thoracis muscle. Some of them must be highlighted, such as: ACSM3 and ACSS1 genes, which work as a precursor in fatty acid synthesis; DGAT2 gene that acts in the deposition of saturated fat in the adipose tissue; GPP and LPL genes that support the synthesis of insulin, stimulating both the glucose synthesis and the amino acids entry into the cells; and the BDH1 gene, which is responsible for the synthesis and degradation of ketone bodies used in the synthesis of ATP. Several genes related to lipid metabolism and fatty acid composition were identified. These findings must contribute to the elucidation of the genetic basis to improve Nellore meat quality traits, with emphasis on human health. Additionally, it can also contribute to improve the knowledge of fatty acid biosynthesis and the selection of animals with better nutritional quality. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 88 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 13 | 15% |
| Student > Master | 11 | 13% |
| Student > Bachelor | 9 | 10% |
| Student > Doctoral Student | 7 | 8% |
| Researcher | 6 | 7% |
| Other | 17 | 19% |
| Unknown | 25 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 33 | 38% |
| Biochemistry, Genetics and Molecular Biology | 10 | 11% |
| Veterinary Science and Veterinary Medicine | 5 | 6% |
| Unspecified | 1 | 1% |
| Medicine and Dentistry | 1 | 1% |
| Other | 2 | 2% |
| Unknown | 36 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 November 2016.
All research outputs
#20,355,479
of 22,903,988 outputs
Outputs from BMC Genomics
#9,300
of 10,674 outputs
Outputs of similar age
#349,453
of 415,669 outputs
Outputs of similar age from BMC Genomics
#187
of 248 outputs
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So far Altmetric has tracked 10,674 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 248 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.