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Poly(ADP-ribose) polymerase 2 contributes to neuroinflammation and neurological dysfunction in mouse experimental autoimmune encephalomyelitis

Overview of attention for article published in Journal of Neuroinflammation, April 2013
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Title
Poly(ADP-ribose) polymerase 2 contributes to neuroinflammation and neurological dysfunction in mouse experimental autoimmune encephalomyelitis
Published in
Journal of Neuroinflammation, April 2013
DOI 10.1186/1742-2094-10-49
Pubmed ID
Authors

Amit Kamboj, Ping Lu, Michael B Cossoy, Jillian L Stobart, Brian A Dolhun, Tiina M Kauppinen, Gilbert de Murcia, Christopher M Anderson

Abstract

Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis characterized by entry of activated T cells and antigen presenting cells into the central nervous system and subsequent autoimmune destruction of nerve myelin. Previous studies revealed that non-selective inhibition of poly(ADP-ribose) polymerases (PARPs) 1 and 2 protect against neuroinflammation and motor dysfunction associated with EAE, but the role of the PARP-2 isoform has not yet been investigated selectively.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 22%
Student > Master 5 19%
Student > Bachelor 3 11%
Student > Ph. D. Student 3 11%
Professor > Associate Professor 2 7%
Other 3 11%
Unknown 5 19%
Readers by discipline Count As %
Medicine and Dentistry 6 22%
Neuroscience 5 19%
Agricultural and Biological Sciences 3 11%
Biochemistry, Genetics and Molecular Biology 2 7%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Other 4 15%
Unknown 6 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 April 2013.
All research outputs
#18,337,420
of 22,708,120 outputs
Outputs from Journal of Neuroinflammation
#2,054
of 2,612 outputs
Outputs of similar age
#148,487
of 196,447 outputs
Outputs of similar age from Journal of Neuroinflammation
#24
of 34 outputs
Altmetric has tracked 22,708,120 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,612 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,447 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.