↓ Skip to main content

Chagas' heart disease: gender differences in myocardial damage assessed by cardiovascular magnetic resonance

Overview of attention for article published in Critical Reviews in Diagnostic Imaging, November 2016
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

twitter
17 X users
facebook
2 Facebook pages

Citations

dimensions_citation
24 Dimensions

Readers on

mendeley
62 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Chagas' heart disease: gender differences in myocardial damage assessed by cardiovascular magnetic resonance
Published in
Critical Reviews in Diagnostic Imaging, November 2016
DOI 10.1186/s12968-016-0307-5
Pubmed ID
Authors

Antonildes N. Assunção, Michael Jerosch-Herold, Rodrigo L. Melo, Alejandra V. Mauricio, Liliane Rocha, Jorge A. Torreão, Fabio Fernandes, Barbara M. Ianni, Charles Mady, José A. F. Ramires, Roberto Kalil-Filho, Carlos E. Rochitte

Abstract

Since a male-related higher cardiovascular morbidity and mortality in patients with Chagas' heart disease has been reported, we aimed to investigate gender differences in myocardial damage assessed by cardiovascular magnetic resonance (CMR). Retrospectively, 62 seropositive Chagas' heart disease patients referred to CMR (1.5 T) and with low probability of having significant coronary artery disease were included in this analysis. Amongst both sexes, there was a strong negative correlation between LV ejection fraction and myocardial fibrosis (male r = 0.64, female r = 0.73, both P < 0.001), with males showing significantly greater myocardial fibrosis (P = 0.002) and lower LV ejection fraction (P < 0.001) than females. After adjustment for potential confounders, gender remained associated with myocardial dysfunction, and 53% of the effect was mediated by myocardial fibrosis (P for mediation = 0.004). Also, the transmural pattern was more prevalent among male patients (23.7 vs. 9.9%, P < 0.001) as well as the myocardial heterogeneity or gray zone (2.2 vs. 1.3 g, P = 0.003). We observed gender-related differences in myocardial damage assessed by CMR in patients with Chagas' heart disease. As myocardial fibrosis and myocardial dysfunction are associated to cardiovascular outcomes, our findings might help to understand the poorer prognosis observed in males in Chagas' disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 62 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 11%
Student > Doctoral Student 5 8%
Student > Bachelor 5 8%
Researcher 4 6%
Student > Postgraduate 4 6%
Other 14 23%
Unknown 23 37%
Readers by discipline Count As %
Medicine and Dentistry 23 37%
Agricultural and Biological Sciences 4 6%
Biochemistry, Genetics and Molecular Biology 2 3%
Immunology and Microbiology 2 3%
Nursing and Health Professions 1 2%
Other 5 8%
Unknown 25 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2017.
All research outputs
#3,398,364
of 25,711,518 outputs
Outputs from Critical Reviews in Diagnostic Imaging
#189
of 1,386 outputs
Outputs of similar age
#61,688
of 419,296 outputs
Outputs of similar age from Critical Reviews in Diagnostic Imaging
#4
of 29 outputs
Altmetric has tracked 25,711,518 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,386 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 419,296 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.