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Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia

Overview of attention for article published in Journal of Neuroinflammation, May 2008
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

news
1 news outlet
twitter
4 X users
facebook
2 Facebook pages
googleplus
1 Google+ user

Citations

dimensions_citation
538 Dimensions

Readers on

mendeley
468 Mendeley
citeulike
4 CiteULike
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Title
Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia
Published in
Journal of Neuroinflammation, May 2008
DOI 10.1186/1742-2094-5-15
Pubmed ID
Authors

Christopher J Henry, Yan Huang, Angela Wynne, Mark Hanke, Justin Himler, Michael T Bailey, John F Sheridan, Jonathan P Godbout

Abstract

Activation of the peripheral innate immune system stimulates the secretion of CNS cytokines that modulate the behavioral symptoms of sickness. Excessive production of cytokines by microglia, however, may cause long-lasting behavioral and cognitive complications. The purpose of this study was to determine if minocycline, an anti-inflammatory agent and purported microglial inhibitor, attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 468 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 9 2%
France 1 <1%
Brazil 1 <1%
Netherlands 1 <1%
Russia 1 <1%
China 1 <1%
Japan 1 <1%
Poland 1 <1%
Unknown 452 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 103 22%
Researcher 64 14%
Student > Master 55 12%
Student > Bachelor 47 10%
Student > Doctoral Student 29 6%
Other 76 16%
Unknown 94 20%
Readers by discipline Count As %
Neuroscience 93 20%
Medicine and Dentistry 69 15%
Agricultural and Biological Sciences 69 15%
Biochemistry, Genetics and Molecular Biology 35 7%
Psychology 22 5%
Other 55 12%
Unknown 125 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 May 2022.
All research outputs
#2,835,009
of 26,017,215 outputs
Outputs from Journal of Neuroinflammation
#416
of 2,992 outputs
Outputs of similar age
#7,637
of 90,058 outputs
Outputs of similar age from Journal of Neuroinflammation
#2
of 8 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,992 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 90,058 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.