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The extracellular microscape governs mesenchymal stem cell fate

Overview of attention for article published in Journal of Biological Engineering, November 2016
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Title
The extracellular microscape governs mesenchymal stem cell fate
Published in
Journal of Biological Engineering, November 2016
DOI 10.1186/s13036-016-0037-0
Pubmed ID
Authors

William J. Hadden, Yu Suk Choi

Abstract

Each cell forever interacts with its extracellular matrix (ECM); a stem cell relies on this interaction to guide differentiation. The stiffness, nanotopography, protein composition, stress and strain inherent to any given ECM influences stem cell lineage commitment. This interaction is dynamic, multidimensional and reciprocally evolving through time, and from this concerted exchange the macroscopic tissues that comprise living organisms are formed. Mesenchymal stem cells can give rise to bone, cartilage, tendon and muscle; thus attempts to manipulate their differentiation must heed the physical properties of incredibly complex native microenvironments to realize regenerative goals.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 48 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 23%
Student > Master 7 15%
Student > Doctoral Student 5 10%
Student > Bachelor 5 10%
Researcher 4 8%
Other 5 10%
Unknown 11 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 17%
Engineering 7 15%
Agricultural and Biological Sciences 6 13%
Medicine and Dentistry 5 10%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 8 17%
Unknown 12 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 November 2016.
All research outputs
#20,355,479
of 22,903,988 outputs
Outputs from Journal of Biological Engineering
#235
of 262 outputs
Outputs of similar age
#348,528
of 414,929 outputs
Outputs of similar age from Journal of Biological Engineering
#6
of 6 outputs
Altmetric has tracked 22,903,988 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 262 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 414,929 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.