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X Demographics
Mendeley readers
Attention Score in Context
Title |
Evidence for tankyrases as antineoplastic targets in lung cancer
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Published in |
BMC Cancer, April 2013
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DOI | 10.1186/1471-2407-13-211 |
Pubmed ID | |
Authors |
Alexander M Busch, Kevin C Johnson, Radu V Stan, Aarti Sanglikar, Yashi Ahmed, Ethan Dmitrovsky, Sarah J Freemantle |
Abstract |
New pharmacologic targets are urgently needed to treat or prevent lung cancer, the most common cause of cancer death for men and women. This study identified one such target. This is the canonical Wnt signaling pathway, which is deregulated in cancers, including those lacking adenomatous polyposis coli or β-catenin mutations. Two poly-ADP-ribose polymerase (PARP) enzymes regulate canonical Wnt activity: tankyrase (TNKS) 1 and TNKS2. These enzymes poly-ADP-ribosylate (PARsylate) and destabilize axin, a key component of the β-catenin phosphorylation complex. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 2 | 29% |
Unknown | 5 | 71% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 86% |
Scientists | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 1 | 2% |
Unknown | 51 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 11 | 21% |
Researcher | 10 | 19% |
Student > Master | 9 | 17% |
Student > Bachelor | 7 | 13% |
Student > Postgraduate | 2 | 4% |
Other | 4 | 8% |
Unknown | 9 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 12 | 23% |
Agricultural and Biological Sciences | 10 | 19% |
Biochemistry, Genetics and Molecular Biology | 8 | 15% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 12% |
Chemistry | 3 | 6% |
Other | 4 | 8% |
Unknown | 9 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 January 2020.
All research outputs
#1,772,538
of 22,708,120 outputs
Outputs from BMC Cancer
#273
of 8,259 outputs
Outputs of similar age
#15,524
of 193,061 outputs
Outputs of similar age from BMC Cancer
#1
of 105 outputs
Altmetric has tracked 22,708,120 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,259 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 193,061 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 105 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.