Title |
Fatal varicella pneumonia in an unvaccinated child with Down Syndrome: a case report
|
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Published in |
Italian Journal of Pediatrics, November 2016
|
DOI | 10.1186/s13052-016-0312-1 |
Pubmed ID | |
Authors |
Diletta Valentini, Simona Bianchi, Chiara Di Camillo, Anna Chiara Vittucci, Michaela Veronika Gonfiantini, Rita De Vito, Alberto Villani |
Abstract |
Varicella is an acute infectious disease common during childhood. It has mostly an uncomplicated course in early childhood. Neverthless, it may result in severe complications, especially in particular age groups and clinical conditions. Down Syndrome represents a risk factor for developing complications, because of the frequent comorbidities and their immunodeficiency. A 2-year-old white Caucasian female affected by Down Syndrome was referred to our hospital for cardiac arrest in course of varicella disease. After cardiopulmonary resuscitation and stabilization, her clinical conditions didn't improve and she developed a massive pulmonary hemorrage, which led her to exitus. Mortality due to varicella infection is rare, but it is more common in subjects with immune deficit or chronic pathologies, and in particular age-groups. The importance of the vaccine for preventable infectious diseases is stressed in this paper, in which we present a case of death in an unvaccinated cardiopathic child with Down Syndrome affected by varicella. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 9 | 41% |
United Kingdom | 3 | 14% |
India | 1 | 5% |
Ireland | 1 | 5% |
Netherlands | 1 | 5% |
Unknown | 7 | 32% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 11 | 50% |
Scientists | 8 | 36% |
Practitioners (doctors, other healthcare professionals) | 3 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 31 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 5 | 16% |
Student > Ph. D. Student | 4 | 13% |
Student > Postgraduate | 4 | 13% |
Student > Master | 4 | 13% |
Student > Doctoral Student | 2 | 6% |
Other | 6 | 19% |
Unknown | 6 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 35% |
Nursing and Health Professions | 4 | 13% |
Unspecified | 1 | 3% |
Linguistics | 1 | 3% |
Immunology and Microbiology | 1 | 3% |
Other | 3 | 10% |
Unknown | 10 | 32% |