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Alterations in gene expression in Caenorhabditis elegans associated with organophosphate pesticide intoxication and recovery

Overview of attention for article published in BMC Genomics, April 2013
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3 X users

Citations

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53 Mendeley
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Title
Alterations in gene expression in Caenorhabditis elegans associated with organophosphate pesticide intoxication and recovery
Published in
BMC Genomics, April 2013
DOI 10.1186/1471-2164-14-291
Pubmed ID
Authors

John A Lewis, Elizabeth A Gehman, Christine E Baer, David A Jackson

Abstract

The principal toxicity of acute organophosphate (OP) pesticide poisoning is the disruption of neurotransmission through inhibition of acetylcholinesterase (AChE). However, other mechanisms leading to persistent effects and neurodegeneration remain controversial and difficult to detect. Because Caenorhabditis elegans is relatively resistant to OP lethality--particularly through the inhibition of AChE--studies in this nematode provide an opportunity to observe alterations in global gene expression following OP exposure that cannot be readily observed in less resistant organisms.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
France 1 2%
Unknown 51 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 19%
Student > Master 8 15%
Student > Ph. D. Student 6 11%
Student > Bachelor 4 8%
Professor > Associate Professor 4 8%
Other 10 19%
Unknown 11 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 26%
Biochemistry, Genetics and Molecular Biology 10 19%
Environmental Science 6 11%
Pharmacology, Toxicology and Pharmaceutical Science 4 8%
Medicine and Dentistry 2 4%
Other 5 9%
Unknown 12 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 May 2013.
All research outputs
#16,919,456
of 25,654,806 outputs
Outputs from BMC Genomics
#6,606
of 11,299 outputs
Outputs of similar age
#125,647
of 204,870 outputs
Outputs of similar age from BMC Genomics
#106
of 174 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,299 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 204,870 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 174 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.