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A human Dravet syndrome model from patient induced pluripotent stem cells

Overview of attention for article published in Molecular Brain, May 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#33 of 1,142)
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

news
1 news outlet
twitter
11 X users
patent
6 patents
facebook
2 Facebook pages

Citations

dimensions_citation
114 Dimensions

Readers on

mendeley
194 Mendeley
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Title
A human Dravet syndrome model from patient induced pluripotent stem cells
Published in
Molecular Brain, May 2013
DOI 10.1186/1756-6606-6-19
Pubmed ID
Authors

Norimichi Higurashi, Taku Uchida, Christoph Lossin, Yoshio Misumi, Yohei Okada, Wado Akamatsu, Yoichi Imaizumi, Bo Zhang, Kazuki Nabeshima, Masayuki X Mori, Shutaro Katsurabayashi, Yukiyoshi Shirasaka, Hideyuki Okano, Shinichi Hirose

Abstract

Dravet syndrome is a devastating infantile-onset epilepsy syndrome with cognitive deficits and autistic traits caused by genetic alterations in SCN1A gene encoding the α-subunit of the voltage-gated sodium channel Na(v)1.1. Disease modeling using patient-derived induced pluripotent stem cells (iPSCs) can be a powerful tool to reproduce this syndrome's human pathology. However, no such effort has been reported to date. We here report a cellular model for DS that utilizes patient-derived iPSCs.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 194 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 3 2%
Italy 1 <1%
Brazil 1 <1%
Australia 1 <1%
Spain 1 <1%
United States 1 <1%
Unknown 186 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 46 24%
Student > Ph. D. Student 35 18%
Student > Master 16 8%
Student > Bachelor 14 7%
Other 12 6%
Other 40 21%
Unknown 31 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 44 23%
Neuroscience 37 19%
Medicine and Dentistry 30 15%
Biochemistry, Genetics and Molecular Biology 17 9%
Psychology 11 6%
Other 12 6%
Unknown 43 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 25. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 March 2023.
All research outputs
#1,366,450
of 23,504,791 outputs
Outputs from Molecular Brain
#33
of 1,142 outputs
Outputs of similar age
#11,324
of 194,061 outputs
Outputs of similar age from Molecular Brain
#1
of 12 outputs
Altmetric has tracked 23,504,791 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,142 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,061 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.