Title |
Curcumin: a natural organic component that plays a multi-faceted role in ovarian cancer
|
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Published in |
Journal of Ovarian Research, March 2023
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DOI | 10.1186/s13048-023-01120-6 |
Pubmed ID | |
Authors |
Xiaoping Liu, Mingming Qi, Xidie Li, Jingjin Wang, Mingyuan Wang |
Abstract |
Curcumin, a natural organic component obtained from Curcuma longa's rhizomes, shows abundant anti-tumor, antioxidant and anti-inflammatory pharmacological activities, among others. Notably the anti-tumor activity has aroused widespread attention from scholars worldwide. Numerous studies have reported that curcumin can delay ovarian cancer (OC), increase its sensitivity to chemotherapy, and reduce chemotherapy drugs' side effects. It has been shown considerable anticancer potential by promoting cell apoptosis, suppressing cell cycle progression, inducing autophagy, inhibiting tumor metastasis, and regulating enzyme activity. With an in-depth study of curcumin's anti-OC mechanism, its clinical application will have broader prospects. This review summarizes the latest studies on curcumin's anti-OC activities, and discusses the specific mechanism, hoping to provide references for further research and applications. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Spain | 2 | 40% |
United States | 1 | 20% |
Peru | 1 | 20% |
Unknown | 1 | 20% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 22 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 3 | 14% |
Student > Ph. D. Student | 1 | 5% |
Student > Doctoral Student | 1 | 5% |
Researcher | 1 | 5% |
Unknown | 16 | 73% |
Readers by discipline | Count | As % |
---|---|---|
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 9% |
Medicine and Dentistry | 1 | 5% |
Engineering | 1 | 5% |
Unknown | 18 | 82% |