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Novel therapeutic agents in clinical development for systemic lupus erythematosus

Overview of attention for article published in BMC Medicine, May 2013
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3 X users
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1 Redditor

Citations

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15 Dimensions

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52 Mendeley
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Title
Novel therapeutic agents in clinical development for systemic lupus erythematosus
Published in
BMC Medicine, May 2013
DOI 10.1186/1741-7015-11-120
Pubmed ID
Authors

Natasha Jordan, Pamela MK Lutalo, David P D’Cruz

Abstract

Conventional immunosuppressive therapies have radically transformed patient survival in systemic lupus erythematosus (SLE), but their use is associated with considerable toxicity and a substantial proportion of patients remain refractory to treatment. A more comprehensive understanding of the complexity of SLE immunopathogenesis has evolved over the past decade and has led to the testing of several biologic agents in clinical trials. There is a clear need for new therapeutic agents that overcome these issues, and biologic agents offer exciting prospects as future SLE therapies.An array of promising new therapies are currently emerging or are under development including B-cell depletion therapies, agents targeting B-cell survival factors, blockade of T-cell co-stimulation and anti-cytokine therapies, such as monoclonal antibodies against interleukin-6 and interferon-α.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Unknown 51 98%

Demographic breakdown

Readers by professional status Count As %
Other 12 23%
Researcher 9 17%
Student > Bachelor 7 13%
Student > Master 5 10%
Student > Doctoral Student 4 8%
Other 10 19%
Unknown 5 10%
Readers by discipline Count As %
Medicine and Dentistry 26 50%
Biochemistry, Genetics and Molecular Biology 5 10%
Pharmacology, Toxicology and Pharmaceutical Science 4 8%
Agricultural and Biological Sciences 3 6%
Chemistry 3 6%
Other 4 8%
Unknown 7 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2014.
All research outputs
#13,888,916
of 22,708,120 outputs
Outputs from BMC Medicine
#2,850
of 3,406 outputs
Outputs of similar age
#106,262
of 192,814 outputs
Outputs of similar age from BMC Medicine
#68
of 75 outputs
Altmetric has tracked 22,708,120 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,406 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.5. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 192,814 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.