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Sexual dimorphism in chronic respiratory diseases

Overview of attention for article published in Cell & Bioscience, March 2023
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  • Good Attention Score compared to outputs of the same age (68th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

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5 X users

Citations

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15 Mendeley
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Title
Sexual dimorphism in chronic respiratory diseases
Published in
Cell & Bioscience, March 2023
DOI 10.1186/s13578-023-00998-5
Pubmed ID
Authors

Karosham Diren Reddy, Brian Gregory George Oliver

Abstract

Sex differences in susceptibility, severity, and progression are prevalent for various diseases in multiple organ systems. This phenomenon is particularly apparent in respiratory diseases. Asthma demonstrates an age-dependent pattern of sexual dimorphism. However, marked differences between males and females exist in other pervasive conditions such as chronic obstructive pulmonary disease (COPD) and lung cancer. The sex hormones estrogen and testosterone are commonly considered the primary factors causing sexual dimorphism in disease. However, how they contribute to differences in disease onset between males and females remains undefined. The sex chromosomes are an under-investigated fundamental form of sexual dimorphism. Recent studies highlight key X and Y-chromosome-linked genes that regulate vital cell processes and can contribute to disease-relevant mechanisms. This review summarises patterns of sex differences in asthma, COPD and lung cancer, highlighting physiological mechanisms causing the observed dimorphism. We also describe the role of the sex hormones and present candidate genes on the sex chromosomes as potential factors contributing to sexual dimorphism in disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Professor 2 13%
Student > Ph. D. Student 2 13%
Researcher 2 13%
Student > Postgraduate 2 13%
Professor > Associate Professor 2 13%
Other 1 7%
Unknown 4 27%
Readers by discipline Count As %
Medicine and Dentistry 5 33%
Environmental Science 2 13%
Immunology and Microbiology 2 13%
Biochemistry, Genetics and Molecular Biology 1 7%
Agricultural and Biological Sciences 1 7%
Other 0 0%
Unknown 4 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 May 2023.
All research outputs
#7,574,581
of 23,750,517 outputs
Outputs from Cell & Bioscience
#179
of 1,010 outputs
Outputs of similar age
#130,746
of 416,750 outputs
Outputs of similar age from Cell & Bioscience
#6
of 60 outputs
Altmetric has tracked 23,750,517 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,010 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 416,750 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.