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Moderation effects of serotype on dengue severity across pregnancy status in Mexico

Overview of attention for article published in BMC Infectious Diseases, March 2023
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Title
Moderation effects of serotype on dengue severity across pregnancy status in Mexico
Published in
BMC Infectious Diseases, March 2023
DOI 10.1186/s12879-023-08051-z
Pubmed ID
Authors

Esther Annan, Uyen-Sa D. T. Nguyen, Jesús Treviño, Wan Fairos Wan Yaacob, Sherry Mangla, Ashok Kumar Pathak, Rajesh Nandy, Ubydul Haque

Abstract

Pregnancy increases a woman's risk of severe dengue. To the best of our knowledge, the moderation effect of the dengue serotype among pregnant women has not been studied in Mexico. This study explores how pregnancy interacted with the dengue serotype from 2012 to 2020 in Mexico. Information from 2469 notifying health units in Mexican municipalities was used for this cross-sectional analysis. Multiple logistic regression with interaction effects was chosen as the final model and sensitivity analysis was done to assess potential exposure misclassification of pregnancy status. Pregnant women were found to have higher odds of severe dengue [1.50 (95% CI 1.41, 1.59)]. The odds of dengue severity varied for pregnant women with DENV-1 [1.45, (95% CI 1.21, 1.74)], DENV-2 [1.33, (95% CI 1.18, 1.53)] and DENV-4 [3.78, (95% CI 1.14, 12.59)]. While the odds of severe dengue were generally higher for pregnant women compared with non-pregnant women with DENV-1 and DENV-2, the odds of disease severity were much higher for those infected with the DENV-4 serotype. The effect of pregnancy on severe dengue is moderated by the dengue serotype. Future studies on genetic diversification may potentially elucidate this serotype-specific effect among pregnant women in Mexico.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Librarian 3 18%
Student > Bachelor 3 18%
Unspecified 1 6%
Student > Master 1 6%
Researcher 1 6%
Other 1 6%
Unknown 7 41%
Readers by discipline Count As %
Computer Science 2 12%
Mathematics 2 12%
Arts and Humanities 1 6%
Unspecified 1 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Other 2 12%
Unknown 8 47%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 March 2023.
All research outputs
#19,163,525
of 24,401,594 outputs
Outputs from BMC Infectious Diseases
#5,543
of 8,163 outputs
Outputs of similar age
#285,252
of 408,198 outputs
Outputs of similar age from BMC Infectious Diseases
#121
of 157 outputs
Altmetric has tracked 24,401,594 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,163 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 408,198 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 157 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.