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Reliability of breath by breath spirometry and relative flow-time indices for pulmonary function testing in horses

Overview of attention for article published in BMC Veterinary Research, November 2016
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Title
Reliability of breath by breath spirometry and relative flow-time indices for pulmonary function testing in horses
Published in
BMC Veterinary Research, November 2016
DOI 10.1186/s12917-016-0893-3
Pubmed ID
Authors

K. Burnheim, K. J. Hughes, D. L. Evans, S. L. Raidal

Abstract

Respiratory problems are common in horses, and are often diagnosed as a cause of poor athletic performance. Reliable, accurate and sensitive spirometric tests of airway function in resting horses would assist with the diagnosis of limitations to breathing and facilitate investigations of the effects of various treatments on breathing capacity. The evaluation of respiratory function in horses is challenging and suitable procedures are not widely available to equine practitioners. The determination of relative flow or flow-time measures is used in paediatric patients where compliance may limit conventional pulmonary function techniques. The aim of the current study was to characterise absolute and relative indices of respiratory function in healthy horses during eupnoea (tidal breathing) and carbon dioxide (CO2)-induced hyperpnoea (rebreathing) using a modified mask pneumotrachographic technique well suited to equine practice, and to evaluate the reliability of this technique over three consecutive days. Coefficients of variation, intra-class correlations, mean differences and 95% confidence intervals across all days of testing were established for each parameter. The technique provided absolute measures of respiratory function (respiratory rate, tidal volume, peak inspiratory and expiratory flows, time to peak flow) consistent with previous studies and there was no significant effect of day on any measure of respiratory function. Variability of measurements was decreased during hyperpnea caused by rebreathing CO2, but a number of relative flow-time variables demonstrated good agreement during eupnoeic respiration. The technique was well tolerated by horses and study findings suggest the technique is suitable for evaluation of respiratory function in horses. The use of relative flow-time variables provided reproducible (consistent) results, suggesting the technique may be of use for repeated measures studies in horses during tidal breathing or rebreathing.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 14%
Student > Bachelor 5 14%
Professor > Associate Professor 4 11%
Researcher 3 9%
Student > Ph. D. Student 2 6%
Other 5 14%
Unknown 11 31%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 11 31%
Agricultural and Biological Sciences 5 14%
Medicine and Dentistry 3 9%
Social Sciences 2 6%
Nursing and Health Professions 1 3%
Other 1 3%
Unknown 12 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 December 2016.
All research outputs
#15,398,970
of 22,908,162 outputs
Outputs from BMC Veterinary Research
#1,424
of 3,057 outputs
Outputs of similar age
#250,752
of 416,651 outputs
Outputs of similar age from BMC Veterinary Research
#22
of 44 outputs
Altmetric has tracked 22,908,162 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,057 research outputs from this source. They receive a mean Attention Score of 3.9. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 416,651 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.