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Pros and cons of a prion-like pathogenesis in Parkinson's disease

Overview of attention for article published in BMC Neurology, June 2011
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Title
Pros and cons of a prion-like pathogenesis in Parkinson's disease
Published in
BMC Neurology, June 2011
DOI 10.1186/1471-2377-11-74
Pubmed ID
Authors

Ruediger Hilker, Jonathan M Brotchie, Joab Chapman

Abstract

Parkinson's disease (PD) is a slowly progressive neurodegenerative disorder which affects widespread areas of the brainstem, basal ganglia and cerebral cortex. A number of proteins are known to accumulate in parkinsonian brains including ubiquitin and α-synuclein. Prion diseases are sporadic, genetic or infectious disorders with various clinical and histopathological features caused by prion proteins as infectious proteinaceous particles transmitting a misfolded protein configuration through brain tissue. The most important form is Creutzfeldt-Jakob disease which is associated with a self-propagating pathological precursor form of the prion protein that is physiologically widely distributed in the central nervous system.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 82 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 26 31%
Student > Ph. D. Student 12 14%
Student > Bachelor 8 10%
Professor 5 6%
Student > Doctoral Student 5 6%
Other 17 20%
Unknown 10 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 33%
Medicine and Dentistry 21 25%
Biochemistry, Genetics and Molecular Biology 8 10%
Neuroscience 7 8%
Social Sciences 2 2%
Other 6 7%
Unknown 12 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 November 2011.
All research outputs
#20,192,189
of 22,709,015 outputs
Outputs from BMC Neurology
#2,131
of 2,423 outputs
Outputs of similar age
#106,220
of 114,708 outputs
Outputs of similar age from BMC Neurology
#31
of 31 outputs
Altmetric has tracked 22,709,015 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,423 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 114,708 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.