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Toxoplasma gondii cathepsin proteases are undeveloped prominent vaccine antigens against toxoplasmosis

Overview of attention for article published in BMC Infectious Diseases, May 2013
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Mentioned by

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2 tweeters
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2 Facebook pages

Citations

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25 Dimensions

Readers on

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39 Mendeley
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Title
Toxoplasma gondii cathepsin proteases are undeveloped prominent vaccine antigens against toxoplasmosis
Published in
BMC Infectious Diseases, May 2013
DOI 10.1186/1471-2334-13-207
Pubmed ID
Authors

Guanghui Zhao, Aihua Zhou, Gang Lv, Min Meng, Min Sun, Yang Bai, Yali Han, Lin Wang, Huaiyu Zhou, Hua Cong, Qunli Zhao, Xing-Quan Zhu, Shenyi He

Abstract

Toxoplasma gondii, an obligate intracellular apicomplexan parasite, infects a wide range of warm-blooded animals including humans. T. gondii expresses five members of the C1 family of cysteine proteases, including cathepsin B-like (TgCPB) and cathepsin L-like (TgCPL) proteins. TgCPB is involved in ROP protein maturation and parasite invasion, whereas TgCPL contributes to proteolytic maturation of proTgM2AP and proTgMIC3. TgCPL is also associated with the residual body in the parasitophorous vacuole after cell division has occurred. Both of these proteases are potential therapeutic targets in T. gondii. The aim of this study was to investigate TgCPB and TgCPL for their potential as DNA vaccines against T. gondii.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 3%
Austria 1 3%
Unknown 37 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 21%
Student > Ph. D. Student 6 15%
Student > Master 5 13%
Student > Bachelor 4 10%
Student > Postgraduate 4 10%
Other 4 10%
Unknown 8 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 23%
Veterinary Science and Veterinary Medicine 6 15%
Medicine and Dentistry 6 15%
Biochemistry, Genetics and Molecular Biology 3 8%
Immunology and Microbiology 3 8%
Other 3 8%
Unknown 9 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 June 2013.
All research outputs
#13,873,783
of 21,346,872 outputs
Outputs from BMC Infectious Diseases
#3,782
of 7,270 outputs
Outputs of similar age
#101,427
of 173,754 outputs
Outputs of similar age from BMC Infectious Diseases
#1
of 1 outputs
Altmetric has tracked 21,346,872 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,270 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 173,754 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them