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Fibroblast growth factor 21 potentially inhibits microRNA-33 expression to affect macrophage actions

Overview of attention for article published in Lipids in Health and Disease, December 2016
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  • Above-average Attention Score compared to outputs of the same age and source (52nd percentile)

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Title
Fibroblast growth factor 21 potentially inhibits microRNA-33 expression to affect macrophage actions
Published in
Lipids in Health and Disease, December 2016
DOI 10.1186/s12944-016-0381-6
Pubmed ID
Authors

Yuan Guo, Fei Luo, Yuhong Yi, Danyan Xu

Abstract

Atherosclerosis is a chronic inflammatory disease with complex pathological processes. MicroRNA-33 (miR-33), a novel non-coding RNA that coexpresses with sterol regulatory element-binding proteins (SREBPs), affects macrophage actions to prevent atherosclerosis. Fibroblast growth factor 21 (FGF21) is an important regulator of lipid metabolism, especially for macrophage-related cholesterol export, but the mechanism is not fully studied. Interestingly, FGF21 has been evidenced to prevent atherosclerosis via inhibiting SREBP-2 expression. Therefore, we speculate that FGF21 may be a potential regulator for miR-33 with an aim of insight into novel anti-atherosclerotic mechanisms and research fields.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 10%
Professor > Associate Professor 1 10%
Student > Postgraduate 1 10%
Student > Master 1 10%
Unknown 6 60%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 1 10%
Nursing and Health Professions 1 10%
Neuroscience 1 10%
Medicine and Dentistry 1 10%
Unknown 6 60%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 December 2016.
All research outputs
#14,286,049
of 22,908,162 outputs
Outputs from Lipids in Health and Disease
#683
of 1,450 outputs
Outputs of similar age
#225,046
of 416,469 outputs
Outputs of similar age from Lipids in Health and Disease
#10
of 21 outputs
Altmetric has tracked 22,908,162 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,450 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 416,469 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.