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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Increased expression of OX40 is associated with progressive disease in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis
|
|---|---|
| Published in |
Retrovirology, May 2013
|
| DOI | 10.1186/1742-4690-10-51 |
| Pubmed ID | |
| Authors |
Mineki Saito, Reiko Tanaka, Shiho Arishima, Toshio Matsuzaki, Satoshi Ishihara, Takashi Tokashiki, Yusuke Ohya, Hiroshi Takashima, Fujio Umehara, Shuji Izumo, Yuetsu Tanaka |
| Abstract |
OX40 is a member of the tumor necrosis factor receptor family that is expressed primarily on activated CD4+ T cells and promotes the development of effector and memory T cells. Although OX40 has been reported to be a target gene of human T-cell leukemia virus type-1 (HTLV-1) viral transactivator Tax and is overexpressed in vivo in adult T-cell leukemia (ATL) cells, an association between OX40 and HTLV-1-associated inflammatory disorders, such as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), has not yet been established. Moreover, because abrogation of OX40 signals ameliorates chronic inflammation in animal models of autoimmune disease, novel monoclonal antibodies against OX40 may offer a potential treatment for HTLV-1-associated diseases such as ATL and HAM/TSP. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| United States | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 2% |
| Brazil | 1 | 2% |
| Unknown | 45 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 17% |
| Researcher | 7 | 15% |
| Student > Postgraduate | 4 | 9% |
| Student > Bachelor | 3 | 6% |
| Student > Doctoral Student | 3 | 6% |
| Other | 9 | 19% |
| Unknown | 13 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 30% |
| Agricultural and Biological Sciences | 7 | 15% |
| Immunology and Microbiology | 6 | 13% |
| Neuroscience | 2 | 4% |
| Engineering | 2 | 4% |
| Other | 2 | 4% |
| Unknown | 14 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 May 2013.
All research outputs
#19,942,887
of 25,371,288 outputs
Outputs from Retrovirology
#1,025
of 1,274 outputs
Outputs of similar age
#149,574
of 205,280 outputs
Outputs of similar age from Retrovirology
#22
of 28 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,274 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 205,280 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.