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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Dock3 interaction with a glutamate-receptor NR2D subunit protects neurons from excitotoxicity
|
|---|---|
| Published in |
Molecular Brain, May 2013
|
| DOI | 10.1186/1756-6606-6-22 |
| Pubmed ID | |
| Authors |
Ning Bai, Hideki Hayashi, Tomomi Aida, Kazuhiko Namekata, Takayuki Harada, Masayoshi Mishina, Kohichi Tanaka |
| Abstract |
N-methyl-D-aspartate receptors (NMDARs) are critical for neuronal development and synaptic plasticity. Dysregulation of NMDARs is implicated in neuropsychiatric disorders. Native NMDARs are heteromultimeric protein complexes consisting of NR1 and NR2 subunits. NR2 subunits (NR2A-D) are the major determinants of the functional properties of NMDARs. Most research has focused on NR2A- and/or NR2B-containing receptors. A recent study demonstrated that NR2C- and/or NR2D-containing NMDARs are the primary targets of memantine, a drug that is widely prescribed to treat Alzheimer's disease. Our laboratory demonstrated that memantine prevents the loss of retinal ganglion cells (RGCs) in GLAST glutamate transporter knockout mice, a model of normal tension glaucoma (NTG), suggesting that NR2D-containing receptors may be involved in RGC loss in NTG. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 2% |
| Australia | 1 | 2% |
| Unknown | 42 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 34% |
| Student > Bachelor | 8 | 18% |
| Researcher | 4 | 9% |
| Student > Master | 3 | 7% |
| Student > Doctoral Student | 1 | 2% |
| Other | 4 | 9% |
| Unknown | 9 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 10 | 23% |
| Agricultural and Biological Sciences | 8 | 18% |
| Biochemistry, Genetics and Molecular Biology | 6 | 14% |
| Medicine and Dentistry | 4 | 9% |
| Unspecified | 1 | 2% |
| Other | 3 | 7% |
| Unknown | 12 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 May 2013.
All research outputs
#20,192,189
of 22,709,015 outputs
Outputs from Molecular Brain
#1,094
of 1,103 outputs
Outputs of similar age
#167,968
of 192,836 outputs
Outputs of similar age from Molecular Brain
#12
of 12 outputs
Altmetric has tracked 22,709,015 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,103 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 192,836 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.