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Dysfunction of the mTOR pathway is a risk factor for Alzheimer’s disease

Overview of attention for article published in Acta Neuropathologica Communications, May 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

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8 X users
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2 patents
facebook
1 Facebook page

Readers on

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111 Mendeley
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Title
Dysfunction of the mTOR pathway is a risk factor for Alzheimer’s disease
Published in
Acta Neuropathologica Communications, May 2013
DOI 10.1186/2051-5960-1-3
Pubmed ID
Authors

Sharon C Yates, Amen Zafar, Paul Hubbard, Sheila Nagy, Sarah Durant, Roy Bicknell, Gordon Wilcock, Sharon Christie, Margaret M Esiri, A David Smith, Zsuzsanna Nagy

Abstract

The development of disease-modifying therapies for Alzheimer's disease is hampered by our lack of understanding of the early pathogenic mechanisms and the lack of early biomarkers and risk factors.We have documented the expression pattern of mTOR regulated genes in the frontal cortex of Alzheimer's disease patients. We have also examined the functional integrity of mTOR signaling in peripheral lymphocytes in Alzheimer's disease patients relative to healthy controls.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Unknown 110 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 22 20%
Student > Ph. D. Student 13 12%
Student > Bachelor 12 11%
Student > Master 11 10%
Other 8 7%
Other 19 17%
Unknown 26 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 23%
Neuroscience 16 14%
Medicine and Dentistry 14 13%
Biochemistry, Genetics and Molecular Biology 11 10%
Sports and Recreations 3 3%
Other 14 13%
Unknown 27 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2019.
All research outputs
#3,869,898
of 22,709,015 outputs
Outputs from Acta Neuropathologica Communications
#750
of 1,364 outputs
Outputs of similar age
#33,300
of 193,626 outputs
Outputs of similar age from Acta Neuropathologica Communications
#3
of 25 outputs
Altmetric has tracked 22,709,015 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,364 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.6. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 193,626 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.