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Acute and subacute IL-1β administrations differentially modulate neuroimmune and neurotrophic systems: possible implications for neuroprotection and neurodegeneration

Overview of attention for article published in Journal of Neuroinflammation, May 2013
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Title
Acute and subacute IL-1β administrations differentially modulate neuroimmune and neurotrophic systems: possible implications for neuroprotection and neurodegeneration
Published in
Journal of Neuroinflammation, May 2013
DOI 10.1186/1742-2094-10-59
Pubmed ID
Authors

Cai Song, Ye Zhang, Yilong Dong

Abstract

In Alzheimer's disease, stroke and brain injuries, activated microglia can release proinflammatory cytokines, such as interleukin (IL)-1β. These cytokines may change astrocyte and neurotrophin functions, which influences neuronal survival and induces apoptosis. However, the interaction between neuroinflammation and neurotrophin functions in different brain conditions is unknown. The present study hypothesized that acute and subacute elevated IL-1β differentially modulates glial and neurotrophin functions, which are related to their role in neuroprotection and neurodegeneration.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Russia 1 <1%
Portugal 1 <1%
Poland 1 <1%
Brazil 1 <1%
Unknown 115 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 35 29%
Student > Bachelor 17 14%
Researcher 12 10%
Student > Master 11 9%
Student > Doctoral Student 6 5%
Other 15 13%
Unknown 23 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 22%
Neuroscience 21 18%
Medicine and Dentistry 20 17%
Biochemistry, Genetics and Molecular Biology 5 4%
Psychology 3 3%
Other 14 12%
Unknown 30 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 May 2013.
All research outputs
#18,338,946
of 22,710,079 outputs
Outputs from Journal of Neuroinflammation
#2,053
of 2,612 outputs
Outputs of similar age
#145,417
of 193,543 outputs
Outputs of similar age from Journal of Neuroinflammation
#23
of 32 outputs
Altmetric has tracked 22,710,079 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,612 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 193,543 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.