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Acute and subacute IL-1β administrations differentially modulate neuroimmune and neurotrophic systems: possible implications for neuroprotection and neurodegeneration

Overview of attention for article published in Journal of Neuroinflammation, May 2013
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1 tweeter

Citations

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Title
Acute and subacute IL-1β administrations differentially modulate neuroimmune and neurotrophic systems: possible implications for neuroprotection and neurodegeneration
Published in
Journal of Neuroinflammation, May 2013
DOI 10.1186/1742-2094-10-59
Pubmed ID
Authors

Cai Song, Ye Zhang, Yilong Dong

Abstract

In Alzheimer's disease, stroke and brain injuries, activated microglia can release proinflammatory cytokines, such as interleukin (IL)-1β. These cytokines may change astrocyte and neurotrophin functions, which influences neuronal survival and induces apoptosis. However, the interaction between neuroinflammation and neurotrophin functions in different brain conditions is unknown. The present study hypothesized that acute and subacute elevated IL-1β differentially modulates glial and neurotrophin functions, which are related to their role in neuroprotection and neurodegeneration.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Russia 1 <1%
Portugal 1 <1%
Poland 1 <1%
Brazil 1 <1%
Unknown 101 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 33 31%
Student > Bachelor 15 14%
Researcher 11 10%
Student > Master 10 10%
Student > Doctoral Student 5 5%
Other 15 14%
Unknown 16 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 24%
Neuroscience 20 19%
Medicine and Dentistry 18 17%
Biochemistry, Genetics and Molecular Biology 3 3%
Psychology 3 3%
Other 13 12%
Unknown 23 22%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 May 2013.
All research outputs
#3,074,854
of 4,507,280 outputs
Outputs from Journal of Neuroinflammation
#461
of 659 outputs
Outputs of similar age
#60,293
of 88,881 outputs
Outputs of similar age from Journal of Neuroinflammation
#33
of 41 outputs
Altmetric has tracked 4,507,280 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 659 research outputs from this source. They receive a mean Attention Score of 3.2. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
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We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one is in the 2nd percentile – i.e., 2% of its contemporaries scored the same or lower than it.