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Variance heterogeneity analysis for detection of potentially interacting genetic loci: method and its limitations

Overview of attention for article published in BMC Genomic Data, October 2010
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Title
Variance heterogeneity analysis for detection of potentially interacting genetic loci: method and its limitations
Published in
BMC Genomic Data, October 2010
DOI 10.1186/1471-2156-11-92
Pubmed ID
Authors

Maksim V Struchalin, Abbas Dehghan, Jacqueline CM Witteman, Cornelia van Duijn, Yurii S Aulchenko

Abstract

Presence of interaction between a genotype and certain factor in determination of a trait's value, it is expected that the trait's variance is increased in the group of subjects having this genotype. Thus, test of heterogeneity of variances can be used as a test to screen for potentially interacting single-nucleotide polymorphisms (SNPs). In this work, we evaluated statistical properties of variance heterogeneity analysis in respect to the detection of potentially interacting SNPs in a case when an interaction variable is unknown.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 1%
Australia 1 1%
Brazil 1 1%
United Kingdom 1 1%
Canada 1 1%
Unknown 75 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 23 29%
Researcher 17 21%
Professor 8 10%
Student > Master 7 9%
Student > Bachelor 4 5%
Other 11 14%
Unknown 10 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 42 53%
Biochemistry, Genetics and Molecular Biology 8 10%
Medicine and Dentistry 6 8%
Environmental Science 2 3%
Arts and Humanities 2 3%
Other 6 8%
Unknown 14 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 April 2013.
All research outputs
#22,759,452
of 25,374,647 outputs
Outputs from BMC Genomic Data
#1,008
of 1,204 outputs
Outputs of similar age
#102,533
of 107,995 outputs
Outputs of similar age from BMC Genomic Data
#5
of 5 outputs
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