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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Normal cognition in transgenic BRI2-Aβ mice
|
|---|---|
| Published in |
Molecular Neurodegeneration, May 2013
|
| DOI | 10.1186/1750-1326-8-15 |
| Pubmed ID | |
| Authors |
Jungsu Kim, Paramita Chakrabarty, Amanda Hanna, Amelia March, Dennis W Dickson, David R Borchelt, Todd Golde, Christopher Janus |
| Abstract |
Recent research in Alzheimer's disease (AD) field has been focused on the potential role of the amyloid-β protein that is derived from the transmembrane amyloid precursor protein (APP) in directly mediating cognitive impairment in AD. Transgenic mouse models overexpressing APP develop robust AD-like amyloid pathology in the brain and show various levels of cognitive decline. In the present study, we examined the cognition of the BRI2-Aβ transgenic mouse model in which secreted extracellular Aβ1-40, Aβ1-42 or both Aβ1-40/Aβ1-42 peptides are generated from the BRI-Aβ fusion proteins encoded by the transgenes. BRI2-Aβ mice produce high levels of Aβ peptides and BRI2-Aβ1-42 mice develop amyloid pathology that is similar to the pathology observed in mutant human APP transgenic models. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| United Kingdom | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 179 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 178 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 36 | 20% |
| Student > Bachelor | 36 | 20% |
| Student > Master | 18 | 10% |
| Researcher | 17 | 9% |
| Professor | 9 | 5% |
| Other | 15 | 8% |
| Unknown | 48 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 35 | 20% |
| Biochemistry, Genetics and Molecular Biology | 26 | 15% |
| Agricultural and Biological Sciences | 25 | 14% |
| Medicine and Dentistry | 9 | 5% |
| Psychology | 8 | 4% |
| Other | 22 | 12% |
| Unknown | 54 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 November 2023.
All research outputs
#16,289,619
of 24,769,082 outputs
Outputs from Molecular Neurodegeneration
#787
of 929 outputs
Outputs of similar age
#119,987
of 197,618 outputs
Outputs of similar age from Molecular Neurodegeneration
#5
of 9 outputs
Altmetric has tracked 24,769,082 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 929 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.0. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,618 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.