Title |
Comparative analysis of cancer vaccine settings for the selection of an effective protocol in mice
|
---|---|
Published in |
Journal of Translational Medicine, May 2013
|
DOI | 10.1186/1479-5876-11-120 |
Pubmed ID | |
Authors |
Francesca Kalli, Rodolfo Machiorlatti, Florinda Battaglia, Alessia Parodi, Giuseppina Conteduca, Francesca Ferrera, Michele Proietti, Samuele Tardito, Marina Sanguineti, Enrico Millo, Daniela Fenoglio, Raffaele De Palma, Giorgio Inghirami, Gilberto Filaci |
Abstract |
Cancer vaccines are considered a promising therapeutic approach. However, their clinical results are not yet satisfactory. This may be due to the the difficulty of selection of an efficient tumor associated antigen (TAA) and immunization protocol. Indeed, the weak antigenicity of many TAA impairs the design of robust procedures, therefore a systematic analysis to identify the most efficient TAA is mandatory. Here, we performed a study to compare different gp100 vaccination strategies to identify the best strategy to provide a 100% protection against experimental melanoma in a reproducible manner. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 1 | 50% |
United States | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Chile | 1 | 2% |
India | 1 | 2% |
Italy | 1 | 2% |
Unknown | 54 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 17 | 30% |
Student > Ph. D. Student | 12 | 21% |
Student > Bachelor | 4 | 7% |
Student > Master | 4 | 7% |
Student > Doctoral Student | 3 | 5% |
Other | 8 | 14% |
Unknown | 9 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 25% |
Agricultural and Biological Sciences | 11 | 19% |
Immunology and Microbiology | 9 | 16% |
Biochemistry, Genetics and Molecular Biology | 4 | 7% |
Chemistry | 4 | 7% |
Other | 5 | 9% |
Unknown | 10 | 18% |