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Polyethylene glycol as a cause of anaphylaxis

Overview of attention for article published in Allergy, Asthma & Clinical Immunology, December 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#5 of 753)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

news
7 news outlets
twitter
110 tweeters
facebook
3 Facebook pages
googleplus
141 Google+ users

Citations

dimensions_citation
42 Dimensions

Readers on

mendeley
48 Mendeley
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Title
Polyethylene glycol as a cause of anaphylaxis
Published in
Allergy, Asthma & Clinical Immunology, December 2016
DOI 10.1186/s13223-016-0172-7
Pubmed ID
Authors

Katharina Wylon, Sabine Dölle, Margitta Worm

Abstract

Polyethylene glycols (PEGs) or macrogols are polyether compounds and are widely used as additives in pharmaceuticals, cosmetics, and food. We report on a Caucasian patient experiencing recurrent severe allergic reactions to several drugs. An extensive diagnostic workup including skin prick tests, intradermal tests (IDT) and a double-blind oral challenge was performed to identify the trigger of anaphylaxis. In the present case hypersensitivity to the additive polyethylene glycol was confirmed by an IDT suggesting an Immunoglobulin E-dependent mechanism as a cause of the reaction. Potential life-threatening hypersensitivity reactions to hidden molecules like macrogol may be underdiagnosed. Cases of immediate-type PEG hypersensitivity were reported with increasing frequency. The awareness regarding the allergenic potential of PEG should be raised and a proper product labelling is crucial to prevent PEG mediated hypersensitivity.

Twitter Demographics

The data shown below were collected from the profiles of 110 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 47 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 17%
Researcher 8 17%
Student > Master 6 13%
Other 5 10%
Student > Bachelor 4 8%
Other 9 19%
Unknown 8 17%
Readers by discipline Count As %
Medicine and Dentistry 15 31%
Pharmacology, Toxicology and Pharmaceutical Science 8 17%
Agricultural and Biological Sciences 4 8%
Engineering 2 4%
Immunology and Microbiology 2 4%
Other 5 10%
Unknown 12 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 280. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 October 2021.
All research outputs
#76,613
of 19,200,799 outputs
Outputs from Allergy, Asthma & Clinical Immunology
#5
of 753 outputs
Outputs of similar age
#2,747
of 407,885 outputs
Outputs of similar age from Allergy, Asthma & Clinical Immunology
#1
of 47 outputs
Altmetric has tracked 19,200,799 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 753 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 407,885 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.