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Promoter DNA methylation regulates progranulin expression and is altered in FTLD

Overview of attention for article published in Acta Neuropathologica Communications, May 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

blogs
2 blogs
twitter
4 X users
patent
3 patents

Citations

dimensions_citation
43 Dimensions

Readers on

mendeley
61 Mendeley
citeulike
1 CiteULike
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Title
Promoter DNA methylation regulates progranulin expression and is altered in FTLD
Published in
Acta Neuropathologica Communications, May 2013
DOI 10.1186/2051-5960-1-16
Pubmed ID
Authors

Julia Banzhaf-Strathmann, Rainer Claus, Oliver Mücke, Kristin Rentzsch, Julie van der Zee, Sebastiaan Engelborghs, Peter P De Deyn, Marc Cruts, Christine van Broeckhoven, Christoph Plass, Dieter Edbauer

Abstract

Frontotemporal lobar degeneration (FTLD) is a heterogeneous group of neurodegenerative diseases associated with personality changes and progressive dementia. Loss-of-function mutations in the growth factor progranulin (GRN) cause autosomal dominant FTLD, but so far the pathomechanism of sporadic FTLD is unclear.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Unknown 60 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 25%
Researcher 9 15%
Student > Bachelor 7 11%
Student > Master 7 11%
Student > Doctoral Student 4 7%
Other 9 15%
Unknown 10 16%
Readers by discipline Count As %
Medicine and Dentistry 12 20%
Agricultural and Biological Sciences 12 20%
Neuroscience 8 13%
Biochemistry, Genetics and Molecular Biology 7 11%
Chemistry 4 7%
Other 7 11%
Unknown 11 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2022.
All research outputs
#1,630,064
of 24,143,470 outputs
Outputs from Acta Neuropathologica Communications
#150
of 1,478 outputs
Outputs of similar age
#13,341
of 196,192 outputs
Outputs of similar age from Acta Neuropathologica Communications
#2
of 27 outputs
Altmetric has tracked 24,143,470 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,478 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.3. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,192 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.