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Differential effects of PCSK9 loss of function variants on serum lipid and PCSK9 levels in Caucasian and African Canadian populations

Overview of attention for article published in Lipids in Health and Disease, May 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

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3 X users
patent
11 patents

Citations

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50 Dimensions

Readers on

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61 Mendeley
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Title
Differential effects of PCSK9 loss of function variants on serum lipid and PCSK9 levels in Caucasian and African Canadian populations
Published in
Lipids in Health and Disease, May 2013
DOI 10.1186/1476-511x-12-70
Pubmed ID
Authors

Janice Mayne, Teik Chye Ooi, Angela Raymond, Marion Cousins, Lise Bernier, Thilina Dewpura, Francine Sirois, Majambu Mbikay, Jean Davignon, Michel Chrétien

Abstract

Variants of the secreted glycoprotein, proprotein convertase subtilisin/kexin 9 (PCSK9), associate with both hypo- and hyper-cholesterolemic phenotypes. Herein, we carried out full exonic sequencing of PCSK9 documenting the frequency of single and multiple PCSK9 variations and their effects on serum lipoprotein and PCSK9 levels in Caucasian Canadians.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Netherlands 1 2%
Unknown 59 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 15%
Student > Ph. D. Student 9 15%
Student > Bachelor 9 15%
Researcher 7 11%
Student > Postgraduate 6 10%
Other 13 21%
Unknown 8 13%
Readers by discipline Count As %
Medicine and Dentistry 17 28%
Agricultural and Biological Sciences 15 25%
Biochemistry, Genetics and Molecular Biology 12 20%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Chemistry 2 3%
Other 4 7%
Unknown 9 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 January 2023.
All research outputs
#3,006,988
of 23,577,761 outputs
Outputs from Lipids in Health and Disease
#206
of 1,492 outputs
Outputs of similar age
#25,851
of 195,040 outputs
Outputs of similar age from Lipids in Health and Disease
#1
of 25 outputs
Altmetric has tracked 23,577,761 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,492 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 195,040 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.