Title |
Differential involvement of the gamma-synuclein in cognitive abilities on the model of knockout mice
|
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Published in |
BMC Neuroscience, May 2013
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DOI | 10.1186/1471-2202-14-53 |
Pubmed ID | |
Authors |
Viktor S Kokhan, Gennadiy I Van’kin, Sergey O Bachurin, Inna Yu Shamakina |
Abstract |
Gamma-synuclein is a member of the synuclein family of cytoplasmic, predominantly neuron-specific proteins. Despite numerous evidences for the importance of gamma-synuclein in the control of monoamine homeostasis, cytoskeleton reorganization and chaperone activity, its role in the regulation of cognitive behavior still remain unknown. Our previous study revealed that gamma-synuclein knockout mice are characterized by high habituation scores. Since a number of processes including spatial memory of the environment may affect habituation, in the present study we have carried out behavioral evaluation of spatial and working memory in gamma-synuclein knockout mice. |
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Unknown | 2 | 67% |
Demographic breakdown
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Members of the public | 3 | 100% |
Mendeley readers
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Demographic breakdown
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Student > Bachelor | 6 | 17% |
Researcher | 5 | 14% |
Student > Master | 3 | 8% |
Student > Doctoral Student | 2 | 6% |
Other | 8 | 22% |
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Neuroscience | 2 | 6% |
Other | 6 | 17% |
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