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Intermolecular interactions of the malate synthase of Paracoccidioides spp

Overview of attention for article published in BMC Microbiology, May 2013
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Title
Intermolecular interactions of the malate synthase of Paracoccidioides spp
Published in
BMC Microbiology, May 2013
DOI 10.1186/1471-2180-13-107
Pubmed ID
Authors

Karine Martins de Oliveira, Benedito Rodrigues da Silva Neto, Juliana Alves Parente, Roosevelt Alves da Silva, Guilherme Oliveira Quintino, Aline Raquel Voltan, Maria José Soares Mendes-Giannini, Célia Maria de Almeida Soares, Maristela Pereira

Abstract

The fungus Paracoccidioides spp is the agent of paracoccidioidomycosis (PCM), a pulmonary mycosis acquired by the inhalation of fungal propagules. Paracoccidioides malate synthase (PbMLS) is important in the infectious process of Paracoccidioides spp because the transcript is up-regulated during the transition from mycelium to yeast and in yeast cells during phagocytosis by murine macrophages. In addition, PbMLS acts as an adhesin in Paracoccidioides spp. The evidence for the multifunctionality of PbMLS indicates that it could interact with other proteins from the fungus and host. The objective of this study was to identify and analyze proteins that possibly bind to PbMLS (PbMLS-interacting proteins) because protein interactions are intrinsic to cell processes, and it might be possible to infer the function of a protein through the identification of its ligands.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 27%
Student > Bachelor 4 13%
Professor 3 10%
Researcher 3 10%
Student > Ph. D. Student 3 10%
Other 6 20%
Unknown 3 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 40%
Immunology and Microbiology 6 20%
Biochemistry, Genetics and Molecular Biology 4 13%
Medicine and Dentistry 3 10%
Computer Science 1 3%
Other 0 0%
Unknown 4 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 November 2014.
All research outputs
#14,753,163
of 22,710,079 outputs
Outputs from BMC Microbiology
#1,590
of 3,171 outputs
Outputs of similar age
#115,322
of 194,054 outputs
Outputs of similar age from BMC Microbiology
#23
of 31 outputs
Altmetric has tracked 22,710,079 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,171 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,054 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.