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Impact of mitral geometry and global afterload on improvement of mitral regurgitation after trans-catheter aortic valve implantation

Overview of attention for article published in Echo Research & Practice, September 2016
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

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17 X users

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Title
Impact of mitral geometry and global afterload on improvement of mitral regurgitation after trans-catheter aortic valve implantation
Published in
Echo Research & Practice, September 2016
DOI 10.1530/erp-16-0018
Pubmed ID
Authors

Y. Tayyareci, R. Dworakowski, P. Kogoj, J. Reiken, C. Kenny, P. MacCarthy, O. Wendler, M. J. Monaghan

Abstract

To assess the impact of mitral geometry, left ventricular (LV) remodeling and global LV after-load on mitral regurgitation (MR) after trans-catheter aortic valve implantation (TAVI). 60 patients with at least mild MR who underwent TAVI were evaluated by 3D Echocardiography at baseline, 1 and 6-months post-procedure. The proportional change in MR following TAVI was determined by examining the percentage change in vena contracta (VC) at 6 months. Patients having a significant reduction of at least 30% in VC were defined as good responders (GR) and the remaining patients were defined as poor responders (PR). 6 months post TAVI, 27(45%) patients were GR and 33(55%) were PR. There was a significant decrease in 3DE-derived mitral annular diameter & area(p=0.001), mitral valve tenting area (TA) (p=0.05) and mitral papillary muscle dyssnchyrony index(DSI)(p=0.05) in GR group.3DE- derived LVESV (p=0.016), LV mass(p=0.001) and LV DSI(p=0.001) were also improved 6-months after TAVI. In addition, valvulo-arterial impedance (ZVA) was significantly higher at baseline in patients with PR(p=0.028). 3DE-derived mitral annular area (beta:0.47, p=0.04), mitral papillary DSI(beta:-0.65, p=0.012) and ZVA(beta:0.45, p=0.028) were the strongest independent parameters that could predict the reduction of functional MR after TAVI. GR patients demonstrate more regression in mitral annulus area and diameter after significant decrease in high LVEDP and trans-aortic gradients with TAVI. PR patients appear to have increased baseline ZVA, mitral valve tenting and restriction in mitral valve coaptation. These factors are important in terms of predicting the impact of TAVI on pre-existing MR.

X Demographics

X Demographics

The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 7%
Unknown 13 93%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 21%
Researcher 3 21%
Student > Postgraduate 2 14%
Other 2 14%
Professor 1 7%
Other 1 7%
Unknown 2 14%
Readers by discipline Count As %
Medicine and Dentistry 12 86%
Engineering 1 7%
Unknown 1 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 March 2018.
All research outputs
#3,371,494
of 25,377,790 outputs
Outputs from Echo Research & Practice
#85
of 268 outputs
Outputs of similar age
#55,437
of 348,375 outputs
Outputs of similar age from Echo Research & Practice
#3
of 7 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 268 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.3. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 348,375 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.