Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosis

Overview of attention for article published in Cell Communication and Signaling, March 2019

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RT @renesugar: Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosis https://t.co/86…

08 May 2023

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RT @renesugar: Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosis https://t.co/86…

08 May 2023

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https://t.co/86NlO8HDQT "We found cMyc decreases pyruvate levels by promoting LDHA and PKM2 levels, this can consequently decrease the inhibition to HDAC3 and protect cancer cells from apoptosis."

08 May 2023

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https://t.co/86NlO8HDQT "Synergistically upregulated LDHA, PKM2 levels resulted in low levels of pyruvate, as well as poor patient survival."

08 May 2023

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