Title |
Personalized medicine in psychiatry: problems and promises
|
---|---|
Published in |
BMC Medicine, May 2013
|
DOI | 10.1186/1741-7015-11-132 |
Pubmed ID | |
Authors |
Uzoezi Ozomaro, Claes Wahlestedt, Charles B Nemeroff |
Abstract |
The central theme of personalized medicine is the premise that an individual's unique physiologic characteristics play a significant role in both disease vulnerability and in response to specific therapies. The major goals of personalized medicine are therefore to predict an individual's susceptibility to developing an illness, achieve accurate diagnosis, and optimize the most efficient and favorable response to treatment. The goal of achieving personalized medicine in psychiatry is a laudable one, because its attainment should be associated with a marked reduction in morbidity and mortality. In this review, we summarize an illustrative selection of studies that are laying the foundation towards personalizing medicine in major depressive disorder, bipolar disorder, and schizophrenia. In addition, we present emerging applications that are likely to advance personalized medicine in psychiatry, with an emphasis on novel biomarkers and neuroimaging. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 16% |
India | 5 | 16% |
United Kingdom | 3 | 10% |
Australia | 2 | 6% |
Canada | 2 | 6% |
Netherlands | 2 | 6% |
Germany | 1 | 3% |
Spain | 1 | 3% |
South Africa | 1 | 3% |
Other | 0 | 0% |
Unknown | 9 | 29% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 24 | 77% |
Practitioners (doctors, other healthcare professionals) | 5 | 16% |
Scientists | 2 | 6% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 3 | <1% |
United Kingdom | 3 | <1% |
United States | 3 | <1% |
Spain | 1 | <1% |
South Africa | 1 | <1% |
Unknown | 413 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 63 | 15% |
Researcher | 55 | 13% |
Student > Ph. D. Student | 55 | 13% |
Student > Bachelor | 46 | 11% |
Other | 34 | 8% |
Other | 77 | 18% |
Unknown | 94 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 86 | 20% |
Psychology | 62 | 15% |
Neuroscience | 39 | 9% |
Agricultural and Biological Sciences | 36 | 8% |
Biochemistry, Genetics and Molecular Biology | 34 | 8% |
Other | 58 | 14% |
Unknown | 109 | 26% |