Title |
Characterization of oral bacterial and fungal microbiome in recovered COVID-19 patients
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Published in |
BMC Microbiology, May 2023
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DOI | 10.1186/s12866-023-02872-3 |
Pubmed ID | |
Authors |
Nana Wei, Guangqi Zhu, Tingxiao Zhao, Yan Wang, Haifei Lou, Haoxuan Li, Zhejuan Yang, Zheen Zhang, Qiujing Wang, Mingfang Han, Zhibing Lin, Shibo Li |
Abstract |
COVID-19 has emerged as a global pandemic, challenging the world's economic and health systems. Human oral microbiota comprises the second largest microbial community after the gut microbiota and is closely related to respiratory tract infections; however, oral microbiomes of patients who have recovered from COVID-19 have not yet been thoroughly studied. Herein, we compared the oral bacterial and fungal microbiota after clearance of SARS-CoV-2 in 23 COVID-19 recovered patients to those of 29 healthy individuals. Our results showed that both bacterial and fungal diversity were nearly normalized in recovered patients. The relative abundance of some specific bacteria and fungi, primarily opportunistic pathogens, decreased in recovered patients (RPs), while the abundance of butyrate-producing organisms increased in these patients. Moreover, these differences were still present for some organisms at 12 months after recovery, indicating the need for long-term monitoring of COVID-19 patients after virus clearance. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Mexico | 2 | 11% |
United Kingdom | 1 | 6% |
Spain | 1 | 6% |
Unknown | 14 | 78% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 15 | 83% |
Practitioners (doctors, other healthcare professionals) | 2 | 11% |
Scientists | 1 | 6% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 15 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 3 | 20% |
Student > Ph. D. Student | 1 | 7% |
Librarian | 1 | 7% |
Professor > Associate Professor | 1 | 7% |
Student > Postgraduate | 1 | 7% |
Other | 0 | 0% |
Unknown | 8 | 53% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 3 | 20% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 7% |
Arts and Humanities | 1 | 7% |
Medicine and Dentistry | 1 | 7% |
Neuroscience | 1 | 7% |
Other | 0 | 0% |
Unknown | 8 | 53% |