Title |
Application of a nanotechnology antimicrobial spray to prevent lower urinary tract infection: a multicenter urology trial
|
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Published in |
Journal of Translational Medicine, September 2012
|
DOI | 10.1186/1479-5876-10-s1-s14 |
Pubmed ID | |
Authors |
Wei He, Dongmin Wang, Zhangqun Ye, Weihong Qian, Yan Tao, Xiaofeng Shi, Ling Liu, Jin Chen, Ling Qiu, Peng Wan, Xiaojun Jia, Xia Li, Caixia Gao, Xuexia Ma, Biyan Wen, Nianzhen Chen, Ping Li, Zhengzheng Ren, Li Lan, Siyi Li, Yi Zuo, Hua Zhang, Liming Ma, Yueping Zhang, Zhicong Li, Weiping Su, Qing Yang, Qingli Chen, Xuejing Wang, Zhenni Ye, JP Chen, Wings TY Loo, Louis WC Chow, Adrian YS Yip, Elizabeth LY Ng, Mary NB Cheung, Zhiping Wang |
Abstract |
Catheter-associated urinary tract infection (CAUTI) is a common nosocomial device-associated infection. It is now recognized that the high infection rates were caused by the formation of biofilm on the surface of the catheters that decreases the susceptibility to antibiotics and results in anti-microbial resistance.In this study, we performed an in vitro test to explore the mechanism of biofilm formation and subsequently conducted a multi-center clinical trial to investigate the efficacy of CAUTI prevention with the application of JUC, a nanotechnology antimicrobial spray. |
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Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
Spain | 1 | 1% |
Nigeria | 1 | 1% |
Singapore | 1 | 1% |
Unknown | 80 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 13 | 15% |
Researcher | 13 | 15% |
Student > Doctoral Student | 8 | 10% |
Student > Bachelor | 8 | 10% |
Student > Ph. D. Student | 8 | 10% |
Other | 16 | 19% |
Unknown | 18 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 28 | 33% |
Nursing and Health Professions | 6 | 7% |
Agricultural and Biological Sciences | 6 | 7% |
Biochemistry, Genetics and Molecular Biology | 4 | 5% |
Immunology and Microbiology | 2 | 2% |
Other | 16 | 19% |
Unknown | 22 | 26% |