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The Cholinergic Anti-inflammatory Pathway: A Missing Link in Neuroimmunomodulation

Overview of attention for article published in Molecular Medicine, June 2003
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#30 of 1,208)
  • High Attention Score compared to outputs of the same age (98th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
39 X users
patent
5 patents
facebook
6 Facebook pages
reddit
1 Redditor

Citations

dimensions_citation
564 Dimensions

Readers on

mendeley
515 Mendeley
citeulike
1 CiteULike
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Title
The Cholinergic Anti-inflammatory Pathway: A Missing Link in Neuroimmunomodulation
Published in
Molecular Medicine, June 2003
DOI 10.1007/bf03402177
Pubmed ID
Authors

Valentin A. Pavlov, Hong Wang, Christopher J. Czura, Steven G. Friedman, Kevin J. Tracey

Abstract

This review outlines the mechanisms underlying the interaction between the nervous and immune systems of the host in response to an immune challenge. The main focus is the cholinergic anti-inflammatory pathway, which we recently described as a novel function of the efferent vagus nerve. This pathway plays a critical role in controlling the inflammatory response through interaction with peripheral a7 subunit-containing nicotinic acetylcholine receptors expressed on macrophages. We describe the modulation of systemic and local inflammation by the cholinergic anti-inflammatory pathway and its function as an interface between the brain and the immune system. The clinical implications of this novel mechanism also are discussed.

X Demographics

X Demographics

The data shown below were collected from the profiles of 39 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 515 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 <1%
Netherlands 3 <1%
Germany 2 <1%
Brazil 1 <1%
Canada 1 <1%
Mexico 1 <1%
Denmark 1 <1%
United Kingdom 1 <1%
Spain 1 <1%
Other 3 <1%
Unknown 496 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 93 18%
Researcher 82 16%
Student > Master 71 14%
Student > Bachelor 54 10%
Student > Doctoral Student 24 5%
Other 90 17%
Unknown 101 20%
Readers by discipline Count As %
Medicine and Dentistry 132 26%
Agricultural and Biological Sciences 75 15%
Neuroscience 47 9%
Biochemistry, Genetics and Molecular Biology 30 6%
Engineering 23 4%
Other 84 16%
Unknown 124 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 43. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 March 2024.
All research outputs
#978,929
of 25,646,963 outputs
Outputs from Molecular Medicine
#30
of 1,208 outputs
Outputs of similar age
#877
of 52,526 outputs
Outputs of similar age from Molecular Medicine
#1
of 1 outputs
Altmetric has tracked 25,646,963 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,208 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 52,526 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them