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Breast cancer stem cells: tools and models to rely on

Overview of attention for article published in BMC Cancer, June 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

Mentioned by

blogs
1 blog
patent
4 patents

Citations

dimensions_citation
104 Dimensions

Readers on

mendeley
240 Mendeley
citeulike
1 CiteULike
connotea
1 Connotea
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Title
Breast cancer stem cells: tools and models to rely on
Published in
BMC Cancer, June 2009
DOI 10.1186/1471-2407-9-202
Pubmed ID
Authors

Emmanuelle Charafe-Jauffret, Christophe Ginestier, Daniel Birnbaum

Abstract

There is increasing evidence for the "cancer stem cell (CSC) hypothesis", which holds that cancers are driven by a cellular component that has stem cell properties, including self-renewal, tumorigenicity and multi-lineage differentiation capacity. Researchers and oncologists see in this model an explanation as to why cancer may be so difficult to cure, as well as a promising ground for novel therapeutic strategies. Given the specific stem cell features of self-renewal and differentiation, which drive tumorigenesis and contribute to cellular heterogeneity, each marker and assay designed to isolate and characterize CSCs has to be functionally validated. In this review, we survey tools and markers available or promising to identify breast CSCs. We review the main models used to study breast CSCs and how they challenge the CSC hypothesis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 240 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 6 3%
United Kingdom 5 2%
Netherlands 3 1%
India 3 1%
Spain 2 <1%
France 1 <1%
Chile 1 <1%
Sweden 1 <1%
Australia 1 <1%
Other 11 5%
Unknown 206 86%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 60 25%
Researcher 59 25%
Student > Master 30 13%
Student > Bachelor 16 7%
Professor > Associate Professor 14 6%
Other 51 21%
Unknown 10 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 115 48%
Medicine and Dentistry 53 22%
Biochemistry, Genetics and Molecular Biology 37 15%
Pharmacology, Toxicology and Pharmaceutical Science 4 2%
Engineering 4 2%
Other 13 5%
Unknown 14 6%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 June 2019.
All research outputs
#2,536,231
of 22,710,079 outputs
Outputs from BMC Cancer
#489
of 8,259 outputs
Outputs of similar age
#9,836
of 111,185 outputs
Outputs of similar age from BMC Cancer
#5
of 49 outputs
Altmetric has tracked 22,710,079 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,259 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 111,185 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.