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Interleukin-21 induces the differentiation of human umbilical cord blood CD34-lineage- cells into pseudomature lytic NK cells

Overview of attention for article published in BMC Immunology, August 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

blogs
1 blog

Citations

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12 Dimensions

Readers on

mendeley
29 Mendeley
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1 Connotea
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Title
Interleukin-21 induces the differentiation of human umbilical cord blood CD34-lineage- cells into pseudomature lytic NK cells
Published in
BMC Immunology, August 2009
DOI 10.1186/1471-2172-10-46
Pubmed ID
Authors

Giuseppina Bonanno, Andrea Mariotti, Annabella Procoli, Maria Corallo, Giovanni Scambia, Luca Pierelli, Sergio Rutella

Abstract

Umbilical cord blood (UCB) is enriched with transplantable CD34+ cells. In addition to CD34-expressing haematopoietic stem cells (HSC), human UCB contains a rare population of CD34-lineage- cells endowed with the ability to differentiate along the T/NK pathway in response to interleukin (IL)-15 and a stromal cell support. IL-21 is a crucial regulator of NK cell function, whose influence on IL-15-induced differentiation of CD34-lineage- cells has not been investigated previously. The present study was designed and conducted to address whether IL-21 might replace the stromal cell requirements and foster the IL-15-induced NK differentiation of human UCB CD34-lineage- cells.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Sweden 1 3%
Canada 1 3%
Unknown 27 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 31%
Researcher 4 14%
Student > Doctoral Student 3 10%
Professor 2 7%
Student > Bachelor 1 3%
Other 3 10%
Unknown 7 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 38%
Immunology and Microbiology 5 17%
Medicine and Dentistry 2 7%
Business, Management and Accounting 1 3%
Sports and Recreations 1 3%
Other 3 10%
Unknown 6 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 August 2010.
All research outputs
#5,394,110
of 22,710,079 outputs
Outputs from BMC Immunology
#79
of 588 outputs
Outputs of similar age
#24,487
of 90,385 outputs
Outputs of similar age from BMC Immunology
#3
of 5 outputs
Altmetric has tracked 22,710,079 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 588 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 90,385 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.