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Mendeley readers
Attention Score in Context
| Title |
Aquaporins: relevance to cerebrospinal fluid physiology and therapeutic potential in hydrocephalus
|
|---|---|
| Published in |
Fluids and Barriers of the CNS, September 2010
|
| DOI | 10.1186/1743-8454-7-15 |
| Pubmed ID | |
| Authors |
Brian K Owler, Tom Pitham, Dongwei Wang |
| Abstract |
The discovery of a family of membrane water channel proteins called aquaporins, and the finding that aquaporin 1 was located in the choroid plexus, has prompted interest in the role of aquaporins in cerebrospinal fluid (CSF) production and consequently hydrocephalus. While the role of aquaporin 1 in choroidal CSF production has been demonstrated, the relevance of aquaporin 1 to the pathophysiology of hydrocephalus remains debated. This has been further hampered by the lack of a non-toxic specific pharmacological blocking agent for aquaporin 1. In recent times aquaporin 4, the most abundant aquaporin within the brain itself, which has also been shown to have a role in brain water physiology and relevance to brain oedema in trauma and tumours, has become an alternative focus of attention for hydrocephalus research. This review summarises current knowledge and concepts in relation to aquaporins, specifically aquaporin 1 and 4, and hydrocephalus. It also examines the relevance of aquaporins as potential therapeutic targets in hydrocephalus and other CSF circulation disorders. |
Mendeley readers
The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 2 | 2% |
| Portugal | 1 | 1% |
| Australia | 1 | 1% |
| Unknown | 88 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 13 | 14% |
| Student > Ph. D. Student | 11 | 12% |
| Professor > Associate Professor | 9 | 10% |
| Researcher | 8 | 9% |
| Student > Doctoral Student | 7 | 8% |
| Other | 21 | 23% |
| Unknown | 23 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 23 | 25% |
| Neuroscience | 15 | 16% |
| Agricultural and Biological Sciences | 15 | 16% |
| Biochemistry, Genetics and Molecular Biology | 5 | 5% |
| Engineering | 3 | 3% |
| Other | 7 | 8% |
| Unknown | 24 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 April 2012.
All research outputs
#22,764,772
of 25,377,790 outputs
Outputs from Fluids and Barriers of the CNS
#433
of 496 outputs
Outputs of similar age
#100,819
of 106,130 outputs
Outputs of similar age from Fluids and Barriers of the CNS
#5
of 5 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 496 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 106,130 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one.