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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Exploring the in vivo wound healing effects of a recombinant hemolin from the caterpillar Lonomia obliqua
|
|---|---|
| Published in |
Journal of Venomous Animals and Toxins including Tropical Diseases, December 2016
|
| DOI | 10.1186/s40409-016-0093-4 |
| Pubmed ID | |
| Authors |
Ana Claudia Sato, Rosemary Viola Bosch, Sonia Elisabete Alves Will, Miryam Paola Alvarez-Flores, Mauricio Barbugiani Goldfeder, Kerly Fernanda Mesquita Pasqualoto, Bárbara Athayde Vaz Galvão da Silva, Sonia Aparecida de Andrade, Ana Marisa Chudzinski-Tavassi |
| Abstract |
Hemolin proteins are cell adhesion molecules from lepidopterans involved in a wide range of cell interactions concerning their adhesion properties. However, hemolin's roles in cell proliferation and wound healing are not fully elucidated. It has been recently reported that rLosac, a recombinant hemolin from the caterpillar Lonomia obliqua, presents antiapoptotic activity and is capable of improving in vitro wound healing. Therefore, this study aimed to explore rLosac's in vivo effects using a skin wound healing model in rats. Circular full-thickness wounds in the rat dorsum skin were treated either with rLosac, or with saline (control), allowing healing by keeping the wounds occluded and moist. During the wound healing, the following tissue regeneration parameters were evaluated: wound closure and collagen content. Furthermore, tissue sections were subjected to histological and immunohistochemical analyses. The rLosac treatment has demonstrated its capacity to improve wound healing, as reflected in findings of a larger number of activated fibroblasts, proliferation of epithelial cells, increase of collagen type 1, and decrease of inflammatory infiltrate. The findings have indicated the rLosac protein as a very promising molecule for the development of new wound-healing formulations. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 33% |
| Australia | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 31 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Unspecified | 7 | 23% |
| Student > Doctoral Student | 4 | 13% |
| Student > Master | 4 | 13% |
| Student > Ph. D. Student | 4 | 13% |
| Researcher | 3 | 10% |
| Other | 3 | 10% |
| Unknown | 6 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Unspecified | 7 | 23% |
| Medicine and Dentistry | 6 | 19% |
| Biochemistry, Genetics and Molecular Biology | 3 | 10% |
| Agricultural and Biological Sciences | 2 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
| Other | 4 | 13% |
| Unknown | 8 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 November 2021.
All research outputs
#6,409,304
of 25,371,288 outputs
Outputs from Journal of Venomous Animals and Toxins including Tropical Diseases
#102
of 539 outputs
Outputs of similar age
#107,592
of 422,577 outputs
Outputs of similar age from Journal of Venomous Animals and Toxins including Tropical Diseases
#3
of 8 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 539 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 422,577 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.