You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Title |
Thirty years on: HIV receptor gymnastics and the prevention of infection
|
---|---|
Published in |
BMC Biology, May 2013
|
DOI | 10.1186/1741-7007-11-57 |
Pubmed ID | |
Authors |
Robin A Weiss |
Abstract |
During 30 years of research on human immunodeficiency virus (HIV), our knowledge of its cellular receptors--CD4, CCR5 and CXCR4--has illuminated aspects of the pathogenesis of the acquired immune deficiency syndrome (AIDS). Studying how the HIV envelope glycoproteins interact with the receptors led to anti-retroviral drugs based on blocking the docking or fusion of virus to the host cell. Genetic polymorphisms of CCR5 determine resistance to HIV infection and the rate of progression to AIDS. Eliciting neutralizing antibodies to the sites of receptor interaction on HIV glycoproteins is a promising approach to HIV vaccine development. |
X Demographics
The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 18% |
United States | 2 | 12% |
Mexico | 2 | 12% |
Canada | 1 | 6% |
France | 1 | 6% |
Peru | 1 | 6% |
Unknown | 7 | 41% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 12 | 71% |
Science communicators (journalists, bloggers, editors) | 3 | 18% |
Practitioners (doctors, other healthcare professionals) | 2 | 12% |
Mendeley readers
The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Malaysia | 1 | 1% |
Portugal | 1 | 1% |
Unknown | 85 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 16 | 18% |
Student > Ph. D. Student | 15 | 17% |
Researcher | 13 | 15% |
Student > Master | 9 | 10% |
Student > Postgraduate | 8 | 9% |
Other | 13 | 15% |
Unknown | 13 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 27 | 31% |
Medicine and Dentistry | 14 | 16% |
Biochemistry, Genetics and Molecular Biology | 14 | 16% |
Immunology and Microbiology | 6 | 7% |
Chemistry | 5 | 6% |
Other | 5 | 6% |
Unknown | 16 | 18% |