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Polyphenol-rich pomegranate fruit extract (POMx) suppresses PMACI-induced expression of pro-inflammatory cytokines by inhibiting the activation of MAP Kinases and NF-κB in human KU812 cells

Overview of attention for article published in Journal of Inflammation, January 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#10 of 425)
  • High Attention Score compared to outputs of the same age (95th percentile)

Mentioned by

news
1 news outlet
twitter
6 X users
patent
2 patents

Readers on

mendeley
96 Mendeley
connotea
1 Connotea
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Title
Polyphenol-rich pomegranate fruit extract (POMx) suppresses PMACI-induced expression of pro-inflammatory cytokines by inhibiting the activation of MAP Kinases and NF-κB in human KU812 cells
Published in
Journal of Inflammation, January 2009
DOI 10.1186/1476-9255-6-1
Pubmed ID
Authors

Zafar Rasheed, Nahid Akhtar, Arivarasu N Anbazhagan, Sangeetha Ramamurthy, Meenakshi Shukla, Tariq M Haqqi

Abstract

Mast cells and basophils are multifunctional effector cells and contain plentiful secretary granules in their cytoplasm. These cell types are involved in several inflammatory and immune events and are known to produce an array of mediators including a broad spectrum of cytokines. Pomegranate fruit is rich in anthocyanins and hydrolysable tannins; a group of polyphenolic compounds shown to be potent antioxidant with anti-inflammatory activity. However, no studies have been undertaken to investigate whether a polyphenol-rich pomegranate fruit extract (POMx) inhibits the inflammatory activity of activated human mast cells and basophils. The aim of this study was to examine whether POMx modulates inflammatory reactions using human basophilic cell line KU812.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 96 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
India 1 1%
Portugal 1 1%
Spain 1 1%
Mauritius 1 1%
Unknown 90 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 19 20%
Student > Master 13 14%
Student > Ph. D. Student 11 11%
Student > Bachelor 8 8%
Student > Doctoral Student 6 6%
Other 19 20%
Unknown 20 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 24%
Medicine and Dentistry 15 16%
Nursing and Health Professions 7 7%
Pharmacology, Toxicology and Pharmaceutical Science 5 5%
Biochemistry, Genetics and Molecular Biology 4 4%
Other 20 21%
Unknown 22 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 January 2023.
All research outputs
#1,858,083
of 25,457,297 outputs
Outputs from Journal of Inflammation
#10
of 425 outputs
Outputs of similar age
#7,703
of 183,580 outputs
Outputs of similar age from Journal of Inflammation
#1
of 2 outputs
Altmetric has tracked 25,457,297 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 425 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 183,580 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them