Title |
Skin appendage-derived stem cells: cell biology and potential for wound repair
|
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Published in |
Burns & Trauma, October 2016
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DOI | 10.1186/s41038-016-0064-6 |
Pubmed ID | |
Authors |
Jiangfan Xie, Bin Yao, Yutong Han, Sha Huang, Xiaobing Fu |
Abstract |
Stem cells residing in the epidermis and skin appendages are imperative for skin homeostasis and regeneration. These stem cells also participate in the repair of the epidermis after injuries, inducing restoration of tissue integrity and function of damaged tissue. Unlike epidermis-derived stem cells, comprehensive knowledge about skin appendage-derived stem cells remains limited. In this review, we summarize the current knowledge of skin appendage-derived stem cells, including their fundamental characteristics, their preferentially expressed biomarkers, and their potential contribution involved in wound repair. Finally, we will also discuss current strategies, future applications, and limitations of these stem cells, attempting to provide some perspectives on optimizing the available therapy in cutaneous repair and regeneration. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 2% |
Unknown | 40 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 20% |
Student > Doctoral Student | 6 | 15% |
Student > Ph. D. Student | 6 | 15% |
Other | 2 | 5% |
Student > Bachelor | 2 | 5% |
Other | 5 | 12% |
Unknown | 12 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 12 | 29% |
Biochemistry, Genetics and Molecular Biology | 7 | 17% |
Agricultural and Biological Sciences | 3 | 7% |
Nursing and Health Professions | 1 | 2% |
Immunology and Microbiology | 1 | 2% |
Other | 3 | 7% |
Unknown | 14 | 34% |