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Skin appendage-derived stem cells: cell biology and potential for wound repair

Overview of attention for article published in Burns & Trauma, October 2016
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Title
Skin appendage-derived stem cells: cell biology and potential for wound repair
Published in
Burns & Trauma, October 2016
DOI 10.1186/s41038-016-0064-6
Pubmed ID
Authors

Jiangfan Xie, Bin Yao, Yutong Han, Sha Huang, Xiaobing Fu

Abstract

Stem cells residing in the epidermis and skin appendages are imperative for skin homeostasis and regeneration. These stem cells also participate in the repair of the epidermis after injuries, inducing restoration of tissue integrity and function of damaged tissue. Unlike epidermis-derived stem cells, comprehensive knowledge about skin appendage-derived stem cells remains limited. In this review, we summarize the current knowledge of skin appendage-derived stem cells, including their fundamental characteristics, their preferentially expressed biomarkers, and their potential contribution involved in wound repair. Finally, we will also discuss current strategies, future applications, and limitations of these stem cells, attempting to provide some perspectives on optimizing the available therapy in cutaneous repair and regeneration.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 2%
Unknown 40 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 20%
Student > Doctoral Student 6 15%
Student > Ph. D. Student 6 15%
Other 2 5%
Student > Bachelor 2 5%
Other 5 12%
Unknown 12 29%
Readers by discipline Count As %
Medicine and Dentistry 12 29%
Biochemistry, Genetics and Molecular Biology 7 17%
Agricultural and Biological Sciences 3 7%
Nursing and Health Professions 1 2%
Immunology and Microbiology 1 2%
Other 3 7%
Unknown 14 34%