Title |
Primary hyperparathyroidism in pregnancy treated with cinacalcet: a case report and review of the literature
|
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Published in |
Journal of Medical Case Reports, December 2016
|
DOI | 10.1186/s13256-016-1093-2 |
Pubmed ID | |
Authors |
Lara Vera, Silvia Oddo, Natascia Di Iorgi, Giorgio Bentivoglio, Massimo Giusti |
Abstract |
The efficacy and safety of various modes of medical treatment for primary hyperparathyroidism in pregnancy are largely unknown. We report the case of a 34-year-old white woman with primary hyperparathyroidism symptomatic for nephrolithiasis. Her serum calcium was 3.15 mmol/l and parathyroid hormone was 109.0 ng/L. Neck imaging found no pathological parathyroid tissue. Cinacalcet and cholecalciferol were started. She became pregnant 17 months later. The calcimimetic was stopped. During pregnancy, she was admitted for hydration administered intravenously two to three times per week. In her 24(th) week of pregnancy, cinacalcet was restarted. In her 32nd week, a cesarean section was carried out as planned. Only three cases of primary hyperparathyroidism in women on cinacalcet therapy in pregnancy have been published in the literature. In the present case, hydration was useful in controlling serum calcium. Cinacalcet therapy helped to control serum calcium. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 2 | 50% |
Serbia | 1 | 25% |
United Kingdom | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 43 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 5 | 12% |
Researcher | 5 | 12% |
Student > Master | 5 | 12% |
Student > Doctoral Student | 3 | 7% |
Professor > Associate Professor | 3 | 7% |
Other | 8 | 19% |
Unknown | 14 | 33% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 16 | 37% |
Social Sciences | 3 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
Nursing and Health Professions | 2 | 5% |
Agricultural and Biological Sciences | 1 | 2% |
Other | 3 | 7% |
Unknown | 16 | 37% |