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Signal transducer and activator of transcription (STAT)-3 regulates microRNA gene expression in chronic lymphocytic leukemia cells

Overview of attention for article published in Molecular Cancer, June 2013
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Title
Signal transducer and activator of transcription (STAT)-3 regulates microRNA gene expression in chronic lymphocytic leukemia cells
Published in
Molecular Cancer, June 2013
DOI 10.1186/1476-4598-12-50
Pubmed ID
Authors

Uri Rozovski, George A Calin, Tetsuro Setoyama, Lucilla D’Abundo, David M Harris, Ping Li, Zhiming Liu, Srdana Grgurevic, Alessandra Ferrajoli, Stefan Faderl, Jan A Burger, Susan O’Brien, William G Wierda, Michael J Keating, Zeev Estrov

Abstract

Approximately 1,000 microRNAs (miRs) are present in the human genome; however, little is known about the regulation of miR transcription. Because miR levels are deregulated in chronic lymphocytic leukemia (CLL) and signal transducer and activator of transcription (STAT)-3 is constitutively activated in CLL, we sought to determine whether STAT3 affects the transcription of miR genes in CLL cells.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Luxembourg 1 2%
Unknown 40 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 24%
Student > Ph. D. Student 8 20%
Student > Master 7 17%
Student > Bachelor 3 7%
Other 2 5%
Other 4 10%
Unknown 7 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 46%
Biochemistry, Genetics and Molecular Biology 5 12%
Medicine and Dentistry 4 10%
Chemistry 2 5%
Immunology and Microbiology 1 2%
Other 1 2%
Unknown 9 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 June 2013.
All research outputs
#14,170,673
of 22,711,242 outputs
Outputs from Molecular Cancer
#900
of 1,716 outputs
Outputs of similar age
#108,517
of 194,186 outputs
Outputs of similar age from Molecular Cancer
#10
of 12 outputs
Altmetric has tracked 22,711,242 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,716 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,186 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.