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Metabolic syndrome, C-reactive protein and microalbuminuria in a rural Chinese population: a cross-sectional study

Overview of attention for article published in BMC Nephrology, June 2013
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Title
Metabolic syndrome, C-reactive protein and microalbuminuria in a rural Chinese population: a cross-sectional study
Published in
BMC Nephrology, June 2013
DOI 10.1186/1471-2369-14-118
Pubmed ID
Authors

Liping Jiang, Wen Huang, Yuanbo Liang, Fenghua Wang, Xinrong Duan, Xiaohui Yang, Jiangping Wen, Ningli Wang

Abstract

BACKGROUND: Microalbuminuria is an early marker of chronic kidney disease (CKD). Previous studies have shown that either metabolic syndrome (MetS) or chronic inflammation is related to renal impairment. The aim of this study was to investigate the association between MetS, C-reactive protein (CRP) and microalbuminuria in a rural Chinese population. METHODS: This was a cross-sectional study using data from the Handan Eye Study. MetS was defined according to the Chinese Diabetes Society (CDS) criteria. CRP levels >= 3 mg/L were classified as high CRP. Microalbuminuria was defined as a urinary albumin/creatinine ratio (ACR) of 30--300 mg/g. RESULTS: We included 4191 subjects aged >= 30 years in this analysis. The prevalence of MetS and microalbuminuria in the group was 25.7% and 15.6%, respectively. The odds ratio (OR) of microalbuminuria in subjects with MetS was 1.25 (95% confidence interval (CI): 1.03 - 1.51) compared with those without microalbuminuria. In multivariate logistic regression analysis, high blood pressure (OR 1.36, 95% CI: 1.10 - 1.67) and high fasting blood glucose (OR 1.44, 95% CI: 1.17 - 1.76) were independently associated with microalbuminuria. Subjects with high CRP and MetS had a 1.46-fold greater risk of having microalbuminuria compared with those with low CRP without MetS (95% CI: 1.06 - 2.01). CONCLUSIONS: In this rural Chinese population aged >=30 years, MetS and microalbuminuria were independently related and the combination of high CRP and MetS was associated with an increased risk of microalbuminuria.

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Mendeley readers

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The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 6%
Unknown 17 94%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 4 22%
Researcher 3 17%
Student > Ph. D. Student 2 11%
Librarian 1 6%
Student > Bachelor 1 6%
Other 1 6%
Unknown 6 33%
Readers by discipline Count As %
Medicine and Dentistry 8 44%
Nursing and Health Professions 3 17%
Agricultural and Biological Sciences 2 11%
Unknown 5 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 June 2013.
All research outputs
#17,689,426
of 22,711,242 outputs
Outputs from BMC Nephrology
#1,694
of 2,456 outputs
Outputs of similar age
#138,033
of 193,471 outputs
Outputs of similar age from BMC Nephrology
#36
of 57 outputs
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