Title |
Chikungunya virus with E1-A226V mutation causing two outbreaks in 2010, Guangdong, China
|
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Published in |
Virology Journal, June 2013
|
DOI | 10.1186/1743-422x-10-174 |
Pubmed ID | |
Authors |
De Wu, Yonghui Zhang, Qiong ZhouHui, Jing Kou, Wenjia Liang, Huan Zhang, Corina Monagin, Qiaoli Zhang, Wenjie Li, Haojie Zhong, Jianfeng He, Hui Li, Songwu Cai, Changwen Ke, Jinyan Lin |
Abstract |
CHIKV is a mosquito-borne emerging pathogen that has a major health impact in humans in tropical zones around the globe. A new variant of the virus, E1-A226V caused a large outbreak in the Indian Ocean islands and India from 2004-2007. CHIKV outbreak was initially reported in Dongguan region of Guangdong in 2010 in China, another smaller CHIKV outbreak was found in Yangjiang region of Guangdong two weeks later. The viral agent causing the two outbreaks was inferred to be the new E1-A226V variant and Yangjiang CHIKV might be introduced from Dongguan. To confirm the hypothesis and determine the origin of CHIKV causing the outbreaks, we described Yangjiang outbreak in this study, and the molecular characterization of CHIKV from Yangjiang and Dongguang outbreaks were analyzed. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 1% |
Vietnam | 1 | 1% |
Unknown | 79 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 14 | 17% |
Student > Ph. D. Student | 9 | 11% |
Student > Doctoral Student | 8 | 10% |
Student > Bachelor | 8 | 10% |
Other | 7 | 9% |
Other | 19 | 23% |
Unknown | 16 | 20% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 13 | 16% |
Biochemistry, Genetics and Molecular Biology | 13 | 16% |
Immunology and Microbiology | 7 | 9% |
Nursing and Health Professions | 2 | 2% |
Other | 8 | 10% |
Unknown | 21 | 26% |