Title |
DEIVA: a web application for interactive visual analysis of differential gene expression profiles
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Published in |
BMC Genomics, January 2017
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DOI | 10.1186/s12864-016-3396-5 |
Pubmed ID | |
Authors |
Jayson Harshbarger, Anton Kratz, Piero Carninci |
Abstract |
Differential gene expression (DGE) analysis is a technique to identify statistically significant differences in RNA abundance for genes or arbitrary features between different biological states. The result of a DGE test is typically further analyzed using statistical software, spreadsheets or custom ad hoc algorithms. We identified a need for a web-based system to share DGE statistical test results, and locate and identify genes in DGE statistical test results with a very low barrier of entry. We have developed DEIVA, a free and open source, browser-based single page application (SPA) with a strong emphasis on being user friendly that enables locating and identifying single or multiple genes in an immediate, interactive, and intuitive manner. By design, DEIVA scales with very large numbers of users and datasets. Compared to existing software, DEIVA offers a unique combination of design decisions that enable inspection and analysis of DGE statistical test results with an emphasis on ease of use. |
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Geographical breakdown
Country | Count | As % |
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Australia | 2 | 18% |
United States | 2 | 18% |
United Kingdom | 2 | 18% |
Germany | 1 | 9% |
Japan | 1 | 9% |
Unknown | 3 | 27% |
Demographic breakdown
Type | Count | As % |
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Scientists | 6 | 55% |
Members of the public | 5 | 45% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 2% |
Unknown | 40 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 13 | 32% |
Student > Bachelor | 6 | 15% |
Student > Doctoral Student | 5 | 12% |
Professor | 3 | 7% |
Other | 3 | 7% |
Other | 10 | 24% |
Unknown | 1 | 2% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 15 | 37% |
Biochemistry, Genetics and Molecular Biology | 13 | 32% |
Computer Science | 4 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Business, Management and Accounting | 1 | 2% |
Other | 4 | 10% |
Unknown | 3 | 7% |