Title |
The RIN: an RNA integrity number for assigning integrity values to RNA measurements
|
---|---|
Published in |
BMC Molecular and Cell Biology, January 2006
|
DOI | 10.1186/1471-2199-7-3 |
Pubmed ID | |
Authors |
Andreas Schroeder, Odilo Mueller, Susanne Stocker, Ruediger Salowsky, Michael Leiber, Marcus Gassmann, Samar Lightfoot, Wolfram Menzel, Martin Granzow, Thomas Ragg |
Abstract |
The integrity of RNA molecules is of paramount importance for experiments that try to reflect the snapshot of gene expression at the moment of RNA extraction. Until recently, there has been no reliable standard for estimating the integrity of RNA samples and the ratio of 28S:18S ribosomal RNA, the common measure for this purpose, has been shown to be inconsistent. The advent of microcapillary electrophoretic RNA separation provides the basis for an automated high-throughput approach, in order to estimate the integrity of RNA samples in an unambiguous way. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 63% |
United Kingdom | 1 | 13% |
Unknown | 2 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 7 | 88% |
Members of the public | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 27 | 1% |
United Kingdom | 15 | <1% |
Germany | 13 | <1% |
Spain | 9 | <1% |
Brazil | 6 | <1% |
Japan | 5 | <1% |
France | 4 | <1% |
Denmark | 4 | <1% |
Chile | 3 | <1% |
Other | 37 | 2% |
Unknown | 2285 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 559 | 23% |
Researcher | 409 | 17% |
Student > Master | 315 | 13% |
Student > Bachelor | 255 | 11% |
Student > Doctoral Student | 148 | 6% |
Other | 312 | 13% |
Unknown | 410 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 888 | 37% |
Biochemistry, Genetics and Molecular Biology | 522 | 22% |
Medicine and Dentistry | 203 | 8% |
Neuroscience | 65 | 3% |
Immunology and Microbiology | 47 | 2% |
Other | 216 | 9% |
Unknown | 467 | 19% |