Title |
Solitary myofibroma of the sigmoid colon: case report and review of the literature
|
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Published in |
Diagnostic Pathology, June 2013
|
DOI | 10.1186/1746-1596-8-90 |
Pubmed ID | |
Authors |
Mi-Jung Kim, Suk Hee Lee, Eui Gon Youk, Sojin Lee, Joon Hyuk Choi, Kyung-Ja Cho |
Abstract |
A 58-year-old woman presented with a solitary myofibroma that arose in the sigmoid colon. Computed tomography revealed a highly enhanced intramural mass (1.3-cm maximum diameter) in the proximal sigmoid colon. Histologically, the tumor exhibited a biphasic growth pattern, which comprised haphazardly arranged, interwoven fascicles of plump, myoid-appearing spindle cells with elongated nuclei and abundant eosinophilic cytoplasm, and more cellular areas of primitive-appearing polygonal cells that were arranged in a hemangiopericytomatous pattern. The tumor cells were positive for smooth muscle actin (SMA), and negative for desmin, h-caldesmon, CD34, cytokeratin, S100 protein, and CD117. The Ki-67 labeling index was not high (up to 7%). Based on these histologic and immunohistochemical features, our patient was diagnosed with a myofibroma of the sigmoid colon. The presence of solitary myofibroma in the intestine of an adult requires attention to avoid misdiagnosis as a more aggressive mesenchymal tumor. |
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Geographical breakdown
Country | Count | As % |
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Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 1 | 11% |
Professor > Associate Professor | 1 | 11% |
Other | 0 | 0% |
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